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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/2074-5044.2023.1.22</article-id><article-id custom-type="elpub" pub-id-type="custom">milmed-206</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ НАУЧНЫЕ ПУБЛИКАЦИИ. Лечебно-профилактические вопросы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL SCIENTIFIC PUBLICATIONS. Medical and preventive questions</subject></subj-group></article-categories><title-group><article-title>Проблема сахарного диабета в лечении вертебральной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>The problem of diabetes in the treatment of vertebral infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корнилов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kornilov</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кунцевич</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuncevich</surname><given-names>M. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеев</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Alexeev</surname><given-names>D. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корнилова</surname><given-names>З. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kornilova</surname><given-names>Z. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земко</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemko</surname><given-names>V. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Витебский государственный ордена Дружбы народов медицинский университет»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>08</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>22</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корнилов А.В., Кунцевич М.В., Алексеев Д.С., Корнилова З.В., Земко В.Ю., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Корнилов А.В., Кунцевич М.В., Алексеев Д.С., Корнилова З.В., Земко В.Ю.</copyright-holder><copyright-holder xml:lang="en">Kornilov A.V., Kuncevich M.V., Alexeev D.S., Kornilova Z.V., Zemko V.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/206">https://milmed.ejournal.by/jour/article/view/206</self-uri><abstract><p>В исследование включено 88 пациентов с вертебральной инфекцией (неспецифический остеомиелит позвоночника M46.3, спинальный эпидуральный абсцесс G06.1), сахарный диабет из которых присутствовал у 24 (27,3%). При наличии у пациента нарушения обмена глюкозы летальность возрастала в 3,9 раза. Ключевым фактором в развитии у пациентов с вертебральной инфекцией тяжелого неврологического дефицита явилось сочетание наличия эпидурита и сахарного диабета. При помощи кластерного анализа было установлено, что наибольшей летальностью (45%) характеризуются пациенты, имеющие помимо воспалительного очага в позвоночнике сахарный диабет, ишемическую болезнь сердца и нефропатию.</p></abstract><trans-abstract xml:lang="en"><p>The study included 88 patients with vertebral infection (nonspecific spinal osteomyelitis M46.3, spinal epidural abscess G06.1), of which 24 (27.3%) had diabetes. If the patient had impaired glucose metabolism, the lethality increased by 3.9 times. A key factor in the development of severe neurological deficit in patients with vertebral infection was the combination of epiduritis and diabetes. With the help of cluster analysis, it was found that the highest mortality (45%) is observed in patients who, in addition to the inflammatory focus in the spine, had diabetes, coronary heart disease and nephropathy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вертебральная инфекция</kwd><kwd>сахарный диабет</kwd><kwd>летальность</kwd><kwd>коморбидная патология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vertebral infection</kwd><kwd>diabetes</kwd><kwd>lethality</kwd><kwd>comorbid pathology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Анализ хирургического лечения остеомиелита позвоночника / И. П. Ардашев [и др.] // Политравма. – 2013. – № 2. – С. 22–29.</mixed-citation><mixed-citation xml:lang="en">Analiz hirurgicheskogo lecheniya osteomielita pozvonochnika / I. P. Ardashev [et al.] // Politravma. – 2013. – № 2. – P. 22–29.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Базаров, А. Ю. Классификация неспецифического гематогенного остеомиелита позвоночника. Критический анализ и предложения по применению / А. Ю. Базаров // Травматология и ортопедия России. – 2019. – № 25(1). – С. 141–155.</mixed-citation><mixed-citation xml:lang="en">Bazarov, A. Yu. Klassifikaciya nespecificheskogo gematogennogo osteomielita pozvonochnika. Kriticheskij analiz i predlozheniya po primeneniyu / A. Yu. Bazarov // Travmatologiya i ortopediya Rossii. – 2019. – № 25 (1). – P. 141–155.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Обзор клинических рекомендаций Американского общества по инфекционным болезням (IDSA) по диагностике и лечению спондилитов у взрослых / И. А. Карпов [и др.] // Клиническая микробиология и антимикробная химиотерапия. – 2017. – Т. 19, № 3. – С. 181–198.</mixed-citation><mixed-citation xml:lang="en">Obzor klinicheskih rekomendacij Amerikanskogo obshchestva po infekcionnym boleznyam (IDSA) po diagnostike i lecheniyu spondilitov u vzroslyh / I. A. Karpov [et al.] // Klinicheskaya mikrobiologiya i antimikrobnaya himioterapiya. – 2017. – Vol. 19, № 3. – P. 181–198.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Pyogenic spondylodiscitis: An overview / G.S. Skaf [et al.] // Journal of Infection and Public Health. – 2010. – № 3. – P. 5–16.</mixed-citation><mixed-citation xml:lang="en">Pyogenic spondylodiscitis: An overview / G.S. Skaf [et al.] // Journal of Infection and Public Health. – 2010. – № 3. – P. 5–16.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">IDF Diabetes Atlas 2021 – 10th edition [Electronic resource] // International Diabetes Federation – Mode of access: https://diabetesatlas.org/idfawp/resource-files/2021/07/IDF_Atlas_10th_Edition_2021.pdf. – Date of access: 10.08.2022.</mixed-citation><mixed-citation xml:lang="en">IDF Diabetes Atlas 2021 – 10th edition [Electronic resource] // International Diabetes Federation – Mode of access: https://diabetesatlas.org/idfawp/resource-files/2021/07/IDF_Atlas_10th_Edition_2021.pdf. – Date of access: 10.08.2022.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dhatariya K. Perioperative diabetes care / K. Dhatariya, N. Levy // Clin. Med. (Lond.). – 2019. – Vol. 19, N 6. – P. 437–440. doi: 10.7861/clinmed.2019.0226.</mixed-citation><mixed-citation xml:lang="en">Dhatariya K. Perioperative diabetes care / K. Dhatariya, N. Levy // Clin. Med. (Lond.). – 2019. – Vol. 19, N 6. – P. 437–440. doi: 10.7861/clinmed.2019.0226.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Подолинский С. Г. Сахарный диабет в практике хирурга и реаниматолога / С. Г. Подолинский, Ю. Б. Мартов, В. Ю. Мартов. – М.: Медицинская литература, 2008. – 288 с.</mixed-citation><mixed-citation xml:lang="en">Podolinskij S. G. Saharnyj diabet v praktike hirurga i reanimatologa / S. G. Podolinskij, Yu. B. Martov, V. Yu. Martov. – M.: Medicinskaya literatura, 2008. – 288 p.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Sudhakaran S. Perioperative Management of the Diabetic Patient [Electronic resource] / S. Sudhakaran, S.R. Surani // Surg. Res. Pract. – 2015. – Article 284063. – Mode of access: https://pubmed.ncbi.nlm.nih.gov/26078998/ – Date of access: 10.08.2022. doi: 10.1155/2015/284063.</mixed-citation><mixed-citation xml:lang="en">Sudhakaran S. Perioperative Management of the Diabetic Patient [Electronic resource] / S. Sudhakaran, S.R. Surani // Surg. Res. Pract. – 2015. – Article 284063. – Mode of access: https://pubmed. ncbi.nlm.nih.gov/26078998/ – Date of access: 10.08.2022. doi: 10.1155/2015/284063.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">CKD-EPI Equations for Glomerular Filtration Rate (GFR) [Electronic resource] / MD+CALC. – Mode of access : https://www.mdcalc.com/calc/3939/ckd-epi-equations-glomerular-filtration-rate-gfr. Date of access : 20.08.2022.</mixed-citation><mixed-citation xml:lang="en">CKD-EPI Equations for Glomerular Filtration Rate (GFR) [Electronic resource] / MD+CALC. – Mode of access : https://www.mdcalc.com/calc/3939/ckd-epi-equations-glomerular-filtration-rate-gfr. Date of access : 20.08.2022.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Вакуум-терапия в хирургическом лечении гнойно-воспалительных заболеваний позвоночника: монография / В.И. Петухов, К.М. Кубраков, А.В. Корнилов. – Витебск: ВГМУ, 2020. – 107 с.</mixed-citation><mixed-citation xml:lang="en">Vakuum-terapiya v hirurgicheskom lechenii gnojno-vospalitel‘nyh zabolevanij pozvonochnika: monografiya / V.I. Petuhov, K.M. Kubrakov, A.V. Kornilov. – Vitebsk: VGMU, 2020. – 107 p.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Сахарный диабет 2-го типа и проблема коморбидной патологии / Г.И. Климентева [и др.] // Кубанский научный медицинский вестник. – 2012. – № 1 (130). – С. 81–84.</mixed-citation><mixed-citation xml:lang="en">Saharnyj diabet 2-go tipa i problema komorbidnoj patologii / G.I. Klimenteva [et al.] // Kubanskij nauchnyj medicinskij vestnik. – 2012. – № 1 (130). – P. 81–84.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
