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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/2074-5044.2023.1.79</article-id><article-id custom-type="elpub" pub-id-type="custom">milmed-232</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Антигипертензивная терапия у пациентов с сахарным диабетом в период пандемии COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Correction of cardiovascular risk factors in patients with arterial hypertension and diabetes mellitus in a time of COVID-19 pandemic</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bova</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>Y. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Метельский</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Metelsky</surname><given-names>S. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Кафедра военно-полевой терапии Военно-медицинский институт в УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>08</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>79</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бова А.А., Громова Ю.М., Метельский С.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Бова А.А., Громова Ю.М., Метельский С.М.</copyright-holder><copyright-holder xml:lang="en">Bova A.A., Gromova Y.M., Metelsky S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/232">https://milmed.ejournal.by/jour/article/view/232</self-uri><abstract><p>Артериальная гипертензия и сахарный диабет установленные большие факторы риска сердечно-сосудистых заболеваний, ассоциированных с атеросклерозом, являются одними из наиболее распространенных коморбидных состояний у пациентов с коронавирусной инфекцией. Каждая из патологий, а тем более их сочетание, увеличивает сердечно-сосудистый риск, а в случае инфицирования SARS-Cov-2 риск тяжелого течения инфекции и летального исхода. В статье рассмотрены механизмы взаимного отягощения коронавирусной инфекции, артериальной гипертензии и сахарного диабета, приведена новая концепция активации иммунной системы при гипертонии, рассмотрены современные подходы к антигипертензивной терапии у пациентов с сахарным диабетом.</p></abstract><trans-abstract xml:lang="en"><p>Arterial hypertension and diabetes mellitus established large risk factors for cardiovascular diseases associated with atherosclerosis are among the most common comorbidities in patients with coronavirus infection. Each of the pathologies, and especially their combination increases the cardiovascular risk, and in case of SARS-Cov-2 infection, the risk of severe course of infection and mortality. The article discusses the mechanisms of mutual burden of coronavirus infection, arterial hypertension and diabetes mellitus, provides a new concept of activating the immune system in hypertension, considers modern approaches to antihypertensive therapy in patients with diabetes mellitus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>артериальная гипертензия</kwd><kwd>сахарный диабет</kwd><kwd>антигипертензивные препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>arterial hypertension</kwd><kwd>diabetes mellitus</kwd><kwd>antihypertensive drugs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Временные методические рекомендации «Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19), версия 15 (22.02.2022)», утв. МЗ РФ.</mixed-citation><mixed-citation xml:lang="en">Vremennye metodicheskie rekomendacii «Profilaktika, diagnostika i lechenie novoj koronavirusnoj infekcii (COVID-19), versiya 15 (22.02.2022)», utv. MZ RF.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации РКО Артериальная гипертензия у взрослых, 2020. – 136 с.</mixed-citation><mixed-citation xml:lang="en">Klinicheskie rekomendacii RKO Arterial‘naya gipertenziya u vzroslyh, 2020. – 136 s.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Шестакова М.В., Викулова О.К., Исаков М.А., Дедов И.И. Сахарный диабет и COVID-19: анализ клинических исходов по данным регистра сахарного диабета Российской Федерации. Проблемы эндокринологии. – 2020;66(1):35-46. doi: doi.org/10.14341/probl12458</mixed-citation><mixed-citation xml:lang="en">Shestakova M.V., Vikulova O.K., Isakov M.A., Dedov I.I. Saharnyj diabet i COVID-19: analiz klinicheskih iskhodov po dannym registra saharnogo diabeta Rossijskoj Federacii. Problemy endokrinologii. – 2020;66(1):35-46. doi: doi.org/10.14341/probl12458</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal, Volume 39, Issue 33, 01 September 2018, Pages 3021–3104, doi.org/10.1093/eurheartj/ehy339</mixed-citation><mixed-citation xml:lang="en">2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal, Volume 39, Issue 33, 01 September 2018, Pages 3021–3104, doi.org/10.1093/eurheartj/ehy339</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. European Heart Journal (2020) 41, 255323. doi:10.1093/eurheartj/ehz486</mixed-citation><mixed-citation xml:lang="en">2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. European Heart Journal (2020) 41, 255323. doi:10.1093/eurheartj/ehz486</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">ADVANCE Management Committee. Study rationale and design of ADVANCE: action in diabetes and vascular disease – preterax and diamicron MR controlled evaluation. Diabetologia. 2001; 44: 1118-20.</mixed-citation><mixed-citation xml:lang="en">ADVANCE Management Committee. Study rationale and design of ADVANCE: action in diabetes and vascular disease – preterax and diamicron MR controlled evaluation. Diabetologia. 2001; 44: 1118-20.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bornstein SR, Rubino F., Khunti K. et al. Practical recommendations for the management of diabetes in patients with COVID-19. http://www. thelancet.com/diabetes-endocrinology Vol 8 June 2020. – P. 546–550.</mixed-citation><mixed-citation xml:lang="en">Bornstein SR, Rubino F., Khunti K. et al. Practical recommendations for the management of diabetes in patients with COVID-19. http://www.thelancet.com/diabetes-endocrinology Vol 8 June 2020. – P. 546–550.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Caillon A., Zhao K., Klein KO et al. Systolic Blood Pressure at Hospital Admission Is an Important Risk Factor in Models Predicting Outcome of COVID-19 Patients. Am J Hypertens 2021 Apr 2;34(3):282-290. doi: 10.1093/ajh/hpaa225.</mixed-citation><mixed-citation xml:lang="en">Caillon A., Zhao K., Klein KO et al. Systolic Blood Pressure at Hospital Admission Is an Important Risk Factor in Models Predicting Outcome of COVID-19 Patients. Am J Hypertens 2021 Apr 2;34(3):282-290. doi: 10.1093/ajh/hpaa225.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. www.thelancet.com. Published Online March 10, 2022 https://doi.org/10.1016/S0140-6736(21)02796-3</mixed-citation><mixed-citation xml:lang="en">Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. www.thelancet.com. Published Online March 10, 2022 https://doi.org/10.1016/S0140-6736(21)02796-3</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nilsson PM. ACCORD and Risk-Factor Control in Type 2 Diabetes. N Engl J Med 2010; 362:1575- 1585. DOI: 10.1056/NEJMoa1001286.</mixed-citation><mixed-citation xml:lang="en">Nilsson PM. ACCORD and Risk-Factor Control in Type 2 Diabetes. N Engl J Med 2010; 362:1575- 1585. DOI: 10.1056/NEJMoa1001286.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Patrick DM, Van Beusecum JP, Kirabo A. et al. The role of inflammation in hypertension: novel concepts. Curr Opin Physiol. 2021 Feb; 19:92-98. doi: 10.1016/j.cophys.2020.09.016. Epub 2020 Oct 13.</mixed-citation><mixed-citation xml:lang="en">Patrick DM, Van Beusecum JP, Kirabo A. et al. The role of inflammation in hypertension: novel concepts. Curr Opin Physiol. 2021 Feb; 19:92-98. doi: 10.1016/j.cophys.2020.09.016. Epub 2020 Oct 13.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Thakur B., Pallavi Dubey P., Joseph Benitez J. et al. A systematic review and meta-analysis of geographic differences in comorbidities and associated severity and mortality among individuals with COVID-19. Sci Rep 11, 8562 (2021). doi.org/10.1038/s41598-021-88130-w.</mixed-citation><mixed-citation xml:lang="en">Thakur B., Pallavi Dubey P., Joseph Benitez J. et al. A systematic review and meta-analysis of geographic differences in comorbidities and associated severity and mortality among individuals with COVID-19. Sci Rep 11, 8562 (2021). doi.org/10.1038/s41598-021-88130-w.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2022 Feb 5;399(10324):520. doi: 10.1016/S0140-6736(22)00061-7.</mixed-citation><mixed-citation xml:lang="en">Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2022 Feb 5;399(10324):520. doi: 10.1016/S0140-6736(22)00061-7.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
