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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/2074-5044.2024.3.78</article-id><article-id custom-type="elpub" pub-id-type="custom">milmed-316</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Хронический гастрит часть 2. Диагностика. Лечение. Профилактика. Диспансерное наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>CHRONIC GASTRITIS PART 2. DIAGNOSTICS. TREATMENT. PREVENTION. DISPENSARY OBSERVATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагорнов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nagornov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра военно-полевой терапии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра военно-полевой терапии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Януль</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yanul</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра военно-полевой терапии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Криушев</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kriushev</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра военно-полевой терапии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загашвили</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zagashvili</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ВМедИ в УО «БГМУ»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>Консультативно-диагностическая поликлиника ФГКУ «442 ВКГ» Министерства обороны Российской Федерации</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>78</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нагорнов И.В., Бова А.А., Януль А.Н., Криушев П.В., Загашвили И.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Нагорнов И.В., Бова А.А., Януль А.Н., Криушев П.В., Загашвили И.В.</copyright-holder><copyright-holder xml:lang="en">Nagornov I.V., Bova A.A., Yanul A.N., Kriushev P.V., Zagashvili I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/316">https://milmed.ejournal.by/jour/article/view/316</self-uri><abstract><p>Во второй части статьи изложены современные подходы к диагностике и лечению хронического гастрита, методы профилактики и принципы диспансерного наблюдения.</p><p>Прогрессирование хронического гастрита приводит к дегенеративным изменениям в слизистой оболочке желудка – атрофии, кишечной метаплазии, дисплазии. Атрофический гастрит является предраковым заболеванием, поэтому выбор правильной тактики ведения пациента с хроническим гастритом может служить мерой профилактики аденокарциномы желудка.</p></abstract><trans-abstract xml:lang="en"><p>The second part of the article describes modern approaches to the diagnosis and treatment of chronic gastritis, methods of prevention and principles of follow-up.</p><p>The progression of chronic gastritis leads to degenerative changes in the gastric mucosa – atrophy, intestinal metaplasia, dysplasia. Atrophic gastritis is a precancerous disease, therefore, choosing the right management tactics for a patient with chronic gastritis can serve as a preventive measure for gastric adenocarcinoma.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический гастрит</kwd><kwd>Hеlicobacter pylori</kwd><kwd>диспепсия</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic gastritis</kwd><kwd>Helicobacter pylori</kwd><kwd>dyspepsia</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В. Т., Маев И. В., Лапина Т. Л., Федоров Е. Д., Шептулин А. А., Трухманов А. С. , Кононов А. В., Абдулхаков Р. А., Алексеева О. П., Алексеенко С. А., Андреев Д. Н., Баранская Е. К., Дехнич Н. И., Кляритская И. Л., Козлов Р. С., Коган Е. А., Королев М. П., Корочанская Н. В., Курилович С. А., Ливзан М. А., Осипенко М. Ф., Павлов П. В., Пирогов С. С., Сарсенбаева А. С., Симаненков В. И., Тертычный А. С., Ткачев А. В., Успенский Ю. П., Хлынов И. Б., Цуканов В. В. Клинические рекомендации Российской гастроэнтерологической ассоциации и ассоциации «Эндоскопическое общество РЭНДО» по диагностике и лечению гастрита, дуоденита. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2021;31(4):70–99. https://doi.org/10.22416/1382-4376-2021-31-4-70-99.</mixed-citation><mixed-citation xml:lang="en">Ivashkin V. T., Maev I. V., Lapina T. L., Fedorov E. D., Sheptulin A. A., Truhmanov A. S., Kononov A. V., Abdulhakov R. A., Alekseeva O. P., Alekseenko S. A., Andreev D. N., Baranskaya E. K., Dekhnich N. I., Klyaritskaya I. L., Kozlov R. S., Kogan E. A., Korolev M. P., Korochanskaya N. V., Kurilovich S. A., Livzan M. A., Osipenko M. F., Pavlov P. V., Pirogov S. S., Sarsenbaeva A. S., Simanenkov V. I., Tertychnyj A. S., Tkachev A. V., Uspenskij Yu.P., Hlynov I. B., Cukanov V. V. Klinicheskie rekomendacii Rossijskoj gastroenterologicheskoj associacii i associacii «Endoskopicheskoe obshchestvo RENDO» po diagnostike i lecheniyu gastrita, duodenita. Rossijskij zhurnal gastroenterologii, gepatologii, koloproktologii. 2021;31(4):70–99. https://doi.org/10.22416/1382-4376-2021-31-4-70-99.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Клинический протокол «Диагностика и лечение пациентов с заболеваниями органов пищеварения»: постановление Министерства здравоохранения Республики Беларусь от 01.06.2017 № 54.</mixed-citation><mixed-citation xml:lang="en">Klinicheskij protokol «Diagnostika i lechenie pacientov s zabolevaniyami organov pishchevareniya»: postanovlenie Ministerstva zdravoohraneniya Respubliki Belarus’ ot 01.06.2017 № 54.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Силивончик Н. Н., Якубчик Т. Н., Януль А. Н. Helicobacter pylori-2022 // Семейный доктор, Минск, 2022 (4): 16–26.</mixed-citation><mixed-citation xml:lang="en">Silivonchik N. N., Yakubchik T. N., Yanul A. N. Helicobacter pylori-2022 // Semejnyj doktor, Minsk, 2022 (4): 16–26.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Янович О. О. Ассоциация мутаций в гене 23S рРНК Нelicobacter pylori, связанных с резистентностью к кларитромицину, с активностью воспаления и морфологическими изменениями слизистой оболочки желудка / О. О. Янович, Л. П. Титов, М. В. Дорошко // Современные проблемы инфекционной патологии человека: сб. науч. тр. / М-во здравоохр. Респ. Беларусь. РНПЦ эпидемиологии и микробиологии; под ред. В. А. Горбунова. – Минск: Изд. центр БГУ, 2022; Вып. 14: 109–113.</mixed-citation><mixed-citation xml:lang="en">Yanovich O. O. Associaciya mutacij v gene 23S rRNK Nelicobacter pylori, svyazannyh s rezistentnost’yu k klaritromicinu, s aktivnost’yu vospaleniya i morfologicheskimi izmeneniyami slizistoj obolochki zheludka / O. O. Yanovich, L. P. Titov, M. V. Doroshko // Sovremennye problemy infekcionnoj patologii cheloveka: sb. nauch. tr. / M-vo zdravoohr. Resp. Belarus’. RNPC epidemiologii i mikrobiologii; pod red. V. A. Gorbunova. – Minsk: Izd. centr BGU, 2022; Vyp. 14: 109–113.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng H. C., Tsai Y. C., Yang H. B. et al. The corpuspredominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia. Helicobacter. 2017;00: e12385. https://doi.org/10.1111/hel.12385</mixed-citation><mixed-citation xml:lang="en">Cheng H. C., Tsai Y. C., Yang H. B. et al. The corpuspredominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia. Helicobacter. 2017;00: e12385. https://doi.org/10.1111/hel.12385</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kyoto global consensus report on Helicobacter pylori gastritis / K. Sugano [et al.] // Gut. 2015; 64, (9): 1353–1367.</mixed-citation><mixed-citation xml:lang="en">Kyoto global consensus report on Helicobacter pylori gastritis / K. Sugano [et al.] // Gut. 2015; 64, (9): 1353–1367.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lenti M. V., Rugge M., Lahner E., Miceli E., Toh B. H., Genta R. M., De Block C., Hershko C., Di Sabatino A. Autoimmune gastritis // Nat Rev Dis Primers. 2020; 6 (1): 56. DOI: 10.1038/s41572-020-0187-8. PMID: 32647173.</mixed-citation><mixed-citation xml:lang="en">Lenti M. V., Rugge M., Lahner E., Miceli E., Toh B. H., Genta R. M., De Block C., Hershko C., Di Sabatino A. Autoimmune gastritis // Nat Rev Dis Primers. 2020; 6 (1): 56. DOI: 10.1038/s41572-020-0187-8. PMID: 32647173.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Malfertheiner P., Megraud F., Rokkas T. et al. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report // Gut. 2022; 71 (9): 1724–1762.</mixed-citation><mixed-citation xml:lang="en">Malfertheiner P., Megraud F., Rokkas T. et al. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report // Gut. 2022; 71 (9): 1724–1762.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mayo Tsuboi, Ryota Niikura, Yoku Hayakawa, Yoshihiro Hirata, Tetsuo Ushiku, Kazuhiko Koike1 Distinct Features of Autoimmune Gastritis in Patients with OpenType Chronic Gastritis in Japan // Biomedicines. 2020; 8 (10): 419.</mixed-citation><mixed-citation xml:lang="en">Mayo Tsuboi, Ryota Niikura, Yoku Hayakawa, Yoshihiro Hirata, Tetsuo Ushiku, Kazuhiko Koike1 Distinct Features of Autoimmune Gastritis in Patients with OpenType Chronic Gastritis in Japan // Biomedicines. 2020; 8 (10): 419.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pennelli G., Grillo F. Galuppini F., et al. Gastritis: update on etiological features and histological practical approach // Pathologica. 2020; 112: 153-165. https://doi.org/10.32074/1591-951X-163.</mixed-citation><mixed-citation xml:lang="en">Pennelli G., Grillo F. Galuppini F., et al. Gastritis: update on etiological features and histological practical approach // Pathologica. 2020; 112: 153-165. https://doi.org/10.32074/1591-951X-163.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rugge M., Sugano K., Scarpignato C., et al. Gastric cancer prevention targeted on risk assessment: Gastritis OLGA staging // Helicobacter. 2019; 24: e12571. https://doi.org/10.1111/hel.1257148.</mixed-citation><mixed-citation xml:lang="en">Rugge M., Sugano K., Scarpignato C., et al. Gastric cancer prevention targeted on risk assessment: Gastritis OLGA staging // Helicobacter. 2019; 24: e12571. https://doi.org/10.1111/hel.1257148.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
