milmedВоенная медицинаMilitary Medicine2074-5044Белорусский государственный медицинский университетmilmed-397Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESМелатонин и его регулирующее влияние на гормональном, тканевом и клеточном уровняхMelatonin and its regulatory effect on the hormone, tissue and cellular levelsЧумакЗ. В.ChumakZ. V.ШаповалН. В.ShapovalN. V.МанасоваГ. С.ManasovaG. S.КухарН. Н.KukharN. N.ЖовтенкоО. В.ZhovtenkoO. V.УО «Одесский национальный медицинский университет»Ukraine20171910202601107110Copyright © Чумак З.В., Шаповал Н.В., Манасова Г.С., Кухар Н.Н., Жовтенко О.В., 20262026Чумак З.В., Шаповал Н.В., Манасова Г.С., Кухар Н.Н., Жовтенко О.В.Chumak Z.V., Shapoval N.V., Manasova G.S., Kukhar N.N., Zhovtenko O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://milmed.ejournal.by/jour/article/view/397

Проведен анализ ряда работ отечественной и зарубежной литературы, посвященных изучению регуляторного влияния мелатонина на организм. Показана возрастная динамика синтеза мелатонина, определенные механизмы влияния на репродуктивную функцию, антиоксидантные и иммуномодулирующие свойства, участие в процессах канцерогенеза, посредством изменения пролиферативной и апоптозной активности, угнетения активности теломеразы.

The analysis of a number of works of domestic and foreign literature devoted to the study of regulatory impact on melatonin hormone, tissue and cellular levels. Has been shown age dynamics of the synthesis of melatonin, has been highlighted certain mechanisms of influence on the reproductive function, antioxidant and immunomodulatory properties. The results of many studies melatonin has confirmed participation in the carcinogenesis process, by changing the proliferative and apoptotic activity, inhibition of telomerase activity.

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The authors declare that there are no conflicts of interest present.