milmedВоенная медицинаMilitary Medicine2074-5044Белорусский государственный медицинский университетmilmed-470Research ArticleКРАТКИЕ СООБЩЕНИЯBRIEF MESSAGESОсобенности экспрессии ламинина в средней оболочке стенки аорты в норме и при аневризме брюшного отдела аортыFeature of the expression of laminin in an aortic media in normal and abdominal aortic aneurysmЮзефовичН. А.YuzefovichN. A.УО «Белорусский государственный медицинский университет»Belarus20171910202603130136Copyright © Юзефович Н.А., 20262026Юзефович Н.А.Yuzefovich N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://milmed.ejournal.by/jour/article/view/470

Методом иммуногистохимии определен ламинин в средней оболочке стенки брюшного отдела аорты человека в норме в возрастных группах с 1 года до 70 лет у лиц мужского и женского пола и проведен морфометрический анализ количественных параметров его экспрессии. Изучена экспрессия ламинина в разных возрастных группах у мужчин и женщин и установлен характер ее изменений с возрастом в норме. Изучены показатели удельной площади ламинина в средней оболочке стенки аорты на границе с аневризматически измененной зоной. Проведен сравнительный анализ изменений экспрессии ламинина в норме и в пограничной с аневризмой зоне. На основе полученных количественных данных проведен регрессионный анализ.

The using a method of immunohistochemistry allowed to determine an expression of laminin in abdominal part of an aortic media in normal in age groups from 1 to 70 years at men and women was determined. The laminin expression in different age groups at men and women was studied and the nature of its changes in normal in different age groups was established. Indicators of the specific area of laminin in aortic media on border from an aneurysm was studied. The comparative analysis of changes of an expression of laminin in normal and in a zone, bordering with aneurism, was carried out. On the basis of the obtained quantitative data the regression analysis was carried out.

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The authors declare that there are no conflicts of interest present.