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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">milmed-501</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ МЕДИЦИНСКОГО ОБЕСПЕЧЕНИЯ ВОЙСК ЗАРУБЕЖНЫХ СТРАН</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ОРГАНИЗАЦИЯ МЕДИЦИНСКОГО ОБЕСПЕЧЕНИЯ ВОЙСК ЗАРУБЕЖНЫХ СТРАН</subject></subj-group></article-categories><title-group><article-title>Поражение нервной системы при ротавирусной инфекции: миф или реальность?</article-title><trans-title-group xml:lang="en"><trans-title>Lesion of nervous system at rotavirus infection: myth or reality?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергиенко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Serhiyenka</surname><given-names>E. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астапов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Astapov</surname><given-names>А. А.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Русанова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rusanova</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашкан</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashkan</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Будрик</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Budrik</surname><given-names>E. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клюйко</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kluiko</surname><given-names>N. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>УЗ «Городская детская инфекционная клиническая больница»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>121</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сергиенко Е.Н., Астапов А.А., Русанова С.А., Кашкан А.М., Будрик Е.А., Клюйко Н.Л., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Сергиенко Е.Н., Астапов А.А., Русанова С.А., Кашкан А.М., Будрик Е.А., Клюйко Н.Л.</copyright-holder><copyright-holder xml:lang="en">Serhiyenka E.N., Astapov А.А., Rusanova S.A., Kashkan A.M., Budrik E.A., Kluiko N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/501">https://milmed.ejournal.by/jour/article/view/501</self-uri><abstract><p>По данным Всемирной организации здравоохранения ежегодно в мире регистрируется более миллиарда диарейных заболеваний, при этом более половины случаев приходится на ранний детский возраст. Вирусные кишечные инфекции играют важную роль в инфекционной заболеваемости у детей различного возраста. Ротавирусная инфекция относится к распространённым вирусным диареям у детей. В структуре острых кишечных инфекций доля ротавирусной инфекции составляет около 30-40%, а в структуре ОКИ с установленным возбудителем – более 50%. Ротавирусная инфекция заканчивается полным выздоровлением пациента при назначении адекватной патогенетической и симптоматической терапии. Всем хорошо известно, что для ротавирусной инфекции типичными являются кишечные проявления. Однако доказан факт генерализации инфекции с поражением различных органов и систем (нервной системы, печени, почек, сердца, поджелудочной железы). В данной статье приводятся клинические случаи, и обсуждается возможность поражения нервной системы при ротавирусной инфекции.</p></abstract><trans-abstract xml:lang="en"><p>According to the World Health Organization, more than a billion diarrheal diseases are registered worldwide each year, with more than half of those occurring in early childhood age. Viral intestinal infections play an important role in infectious diseases in children of different ages. Rotavirus infection refers to the prevalence of viral diarrhea in young children. In acute intestinal infections structure the part of rotavirus infection is about 30–40% (more than 50% amongst intestinal infections with the known agent). In most cases, rotavirus infection ends with a complete recovery of the patient with the appointment of pathogenetic and symptomatic therapy. It is well known that intestinal manifestations are typical for rotavirus infection. However, the fact of generalization of infection with the defeat of various organs and systems (nervous system, liver, kidneys, heart, pancreas) is proved. This article presents a clinical cases and discusses the possibility of damage to the nervous system during rotavirus infection. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>острые кишечные инфекции</kwd><kwd>ротавирусная инфекция</kwd><kwd>нервная система</kwd><kwd>судороги</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute intestinal infections</kwd><kwd>rotavirus infection</kwd><kwd>nervous system</kwd><kwd>convulsive</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Горелов, А. В. Ротавирусная инфекция у детей / А. В. Горелов, Д. В. Усенко // Вопросы современной педиатрии. – № 6, том 8. – С. 78–84.</mixed-citation><mixed-citation xml:lang="en">Горелов, А. В. Ротавирусная инфекция у детей / А. В. Горелов, Д. В. Усенко // Вопросы современной педиатрии. – № 6, том 8. – С. 78–84.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Брико, Н. И. Ротавирусная инфекция: современный взгляд на проблему / Н. И. Брико, А. В. Горелов // Медицинский вестник. – № 14–15. – 2014. – С. 10–11.</mixed-citation><mixed-citation xml:lang="en">Брико, Н. И. Ротавирусная инфекция: современный взгляд на проблему / Н. И. Брико, А. В. Горелов // Медицинский вестник. – № 14–15. – 2014. – С. 10–11.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Acute cerebellitis associated with rotavirus infection / Kato Z. [et. al] // World pediatric journal. – № 9 (1). – 2013. – Р. 87–89.</mixed-citation><mixed-citation xml:lang="en">Acute cerebellitis associated with rotavirus infection / Kato Z. [et. al] // World pediatric journal. – № 9 (1). – 2013. – Р. 87–89.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">A transient lesion in the corpus callosum during rotavirus infection / Kato Z. [et. al] // Pediatric neurological journal. – № 41. – 2009. – Р.467–469.</mixed-citation><mixed-citation xml:lang="en">A transient lesion in the corpus callosum during rotavirus infection / Kato Z. [et. al] // Pediatric neurological journal. – № 41. – 2009. – Р.467–469.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Clinical and radiological features of rotavirus cerebellitis / Takanashi T. [et. al] // American journal of neuroradiology. – № 31 (9). – 2010. – Р. 1591–95.</mixed-citation><mixed-citation xml:lang="en">Clinical and radiological features of rotavirus cerebellitis / Takanashi T. [et. al] // American journal of neuroradiology. – № 31 (9). – 2010. – Р. 1591–95.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nagatomi, T. Rotavirus antigenemia in children with encephalopathy accompanied by rotavirus gastroenteriti / T. Nagatomi, O. Nagatomi // Arch viral journal. – № 150. – 2005. – Р. 1927–31.</mixed-citation><mixed-citation xml:lang="en">Nagatomi, T. Rotavirus antigenemia in children with encephalopathy accompanied by rotavirus gastroenteriti / T. Nagatomi, O. Nagatomi // Arch viral journal. – № 150. – 2005. – Р. 1927–31.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ramig, R. Pathogenesis of intestinal and systemic rotavirus infection / R. Ramig // Virol. journal. – № 78. – 2004. – Р. 10213–20.</mixed-citation><mixed-citation xml:lang="en">Ramig, R. Pathogenesis of intestinal and systemic rotavirus infection / R. Ramig // Virol. journal. – № 78. – 2004. – Р. 10213–20.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ramig, R. F. Systemic rotavirus infection / R. Ramig // Expert rev. anti. infect. journal. – 2007. – № 4 (5). – Р. 591–612.</mixed-citation><mixed-citation xml:lang="en">Ramig, R. F. Systemic rotavirus infection / R. Ramig // Expert rev. anti. infect. journal. – 2007. – № 4 (5). – Р. 591–612.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus and central nervous system symptoms: cause or contaminant? Case reports and review / Lynch M. [et. al] // Clinical infectious diseases journal. – № 33 (7). – 2001. – Р. 932–938.</mixed-citation><mixed-citation xml:lang="en">Rotavirus and central nervous system symptoms: cause or contaminant? Case reports and review / Lynch M. [et. al] // Clinical infectious diseases journal. – № 33 (7). – 2001. – Р. 932–938.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus-associated encephalopathy with a reversible splenial lesion / Fukuda S. [et. al] // Pediatr. neurol. journal. – № 40. – 2009. – Р. 133–133.</mixed-citation><mixed-citation xml:lang="en">Rotavirus-associated encephalopathy with a reversible splenial lesion / Fukuda S. [et. al] // Pediatr. neurol. journal. – № 40. – 2009. – Р. 133–133.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus cerebellitis? / Lise E. [et. al] // Clinical infectious diseases journal. – № 8. – 2002. – Р. 130–135.</mixed-citation><mixed-citation xml:lang="en">Rotavirus cerebellitis? / Lise E. [et. al] // Clinical infectious diseases journal. – № 8. – 2002. – Р. 130–135.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus encephalitis and cerebellitis with reversible magnetic resonance signal changes / Mori T. [et. al] // Pediatric int. journal. – № 53 (2). – 2011. – Р. 252–255.</mixed-citation><mixed-citation xml:lang="en">Rotavirus encephalitis and cerebellitis with reversible magnetic resonance signal changes / Mori T. [et. al] // Pediatric int. journal. – № 53 (2). – 2011. – Р. 252–255.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children: Clinical Analysis of 40 Cases / Jeng-Juh Hung [et. al] // Chang Gung Med J Vol. – № 9 (26). – 2003. – P. 654–58.</mixed-citation><mixed-citation xml:lang="en">Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children: Clinical Analysis of 40 Cases / Jeng-Juh Hung [et. al] // Chang Gung Med J Vol. – № 9 (26). – 2003. – P. 654–58.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Rotavirus meningoencephalitis in a previously healthy child and a review of the literature / Dickey M. [et. al] // Clinical infectious diseases journal. – № 28. – 2009. – Р. 318–321.</mixed-citation><mixed-citation xml:lang="en">Rotavirus meningoencephalitis in a previously healthy child and a review of the literature / Dickey M. [et. al] // Clinical infectious diseases journal. – № 28. – 2009. – Р. 318–321.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Systemic manifestation of rotavirus infection in children: A Report of Three Cases / Akcaboy M. [et. al] // Iranian red crescent medical journal. – № 18 (8). – 2016. – Р. 233–235.</mixed-citation><mixed-citation xml:lang="en">Systemic manifestation of rotavirus infection in children: A Report of Three Cases / Akcaboy M. [et. al] // Iranian red crescent medical journal. – № 18 (8). – 2016. – Р. 233–235.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
