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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">milmed-742</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ НАУЧНЫЕ ПУБЛИКАЦИИ. Военная эпидемиология и гигиена</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL SCIENTIFIC PUBLICATIONS. Military epidemiology and hygiene</subject></subj-group></article-categories><title-group><article-title>Эпидемиологическая характеристика и особенности иммунитета при брюшном тифе</article-title><trans-title-group xml:lang="en"><trans-title>The epidemiological characteristic and immunity features in typhoid fever</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбич</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbich</surname><given-names>O. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Квятковская</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kviatkovskaya</surname><given-names>E. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глинская</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Glinskaya</surname><given-names>I. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бискина</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Biskina</surname><given-names>N. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГУ «Республиканский центр гигиены, эпидемиологии и общественного здоровья»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>36</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Горбич О.А., Квятковская Е.Г., Глинская И.Н., Бискина Н.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Горбич О.А., Квятковская Е.Г., Глинская И.Н., Бискина Н.М.</copyright-holder><copyright-holder xml:lang="en">Gorbich O.A., Kviatkovskaya E.G., Glinskaya I.N., Biskina N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/742">https://milmed.ejournal.by/jour/article/view/742</self-uri><abstract><p>Представлена эпидемиологическая характеристика многолетней и годовой динамик заболеваемости брюшным тифом населения Республики Беларусь за период с 1945 по 2018 гг. Для решения поставленных задач в работе применялись методы эпидемиологической диагностики – ретроспективный эпидемиологический анализ и статистические методы исследования. Заболеваемость брюшным тифом неравномерно распределялась по годам (от 0,01 до 75,8 случаев на 100000 населения). В настоящее время в стране зарегистрировано 77 хронических носителей брюшного тифа, большинство из них женщины, 94,8±2,5 % являются не работающими пенсионерами. Наибольшее число хронических носителей брюшного тифа зарегистрировано в Минской и Брестской областях – 58,4 %, наименьший удельный вес был выявлен на территории Витебской, Гомельской, Могилевской областей и в г. Минске – в пределах 6,5–7,8 %. На территории Республики Беларусь среди хронических носителей наиболее распространены фаготипы А и Е1 – 50,6±1,3 %, удельный вес других фаготипов S. typhi был выявлен в пределах 1,3–10,4 %. Инфицирование брюшным тифом происходило преимущественно в возрасте 18–40 лет (66,3±5,4 %) и в 28,3±5,1 % случаях было связано с контактом с заболевшим брюшным тифом в семье или коллективе.</p></abstract><trans-abstract xml:lang="en"><p>The epidemiological characteristic of the typhoid morbidity annual and long-standing dynamics in population of the Republic of Belarus from 1945 to 2018 was provided. We used the following epidemiological diagnostics methods for meeting the established objectives: the retrospective epidemiological analysis and basic statistical methods. The typhoid morbidity was uneven between different years (from 0.01 to 75.8 cases per 100 000 people). Currently 77 chronic typhoid carriers are registered in the Republic of Belarus. The majority of them are women and 94.8±2.5 % of this carriers are non-working retirees. The vast majority of chronic typhoid carriers are registered in the Minsk and Brest regions (58.4 %), the least of them are found in the Vitebsk, Gomel, Mogilev regions and in Minsk city (ranged from 6.5 % to 7.8 %). In the Republic of Belarus phagotypes A and E1 are the most common in chronic typhoid carriers (50.6±1.3 %). The proportion of the other S. typhi phagotypes varies between 1.3 % and 10.4 %. The predominant age of typhoid infection was 18–40 years old (66.3±5.4 %). In 28.3±5.1 % of cases infection was associated with household or work contact with typhoid fever patient or carrier.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>брюшной тиф</kwd><kwd>носители</kwd><kwd>фаготипы</kwd><kwd>возрастные группы</kwd><kwd>Salmonella typhi</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Typhoid fever</kwd><kwd>carriers</kwd><kwd>phagotypes</kwd><kwd>age groups</kwd><kwd>Salmonella typhi</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Брюшнотифозные вакцины: Документ с изложением позиции ВОЗ [Электронный ресурс] // Всемирная организация здравоохранения. – 2008. – № 6. – Режим доступа: https://www.who.int/immunization/Typhoid_RUS_Mar08.pdf. – Дата доступа: 11.07.2019.</mixed-citation><mixed-citation xml:lang="en">Брюшнотифозные вакцины: Документ с изложением позиции ВОЗ [Электронный ресурс] // Всемирная организация здравоохранения. – 2008. – № 6. – Режим доступа: https://www.who.int/immunization/Typhoid_RUS_Mar08.pdf. – Дата доступа: 11.07.2019.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines on the quality, safety and efficacy of typhoid conjugate vaccines [Electronic resource] // World Health Organization. – Mode of access: https://www.who.int/immunization/diseases/typhoid/ru/. – Date of access: 15.07.2019.</mixed-citation><mixed-citation xml:lang="en">Guidelines on the quality, safety and efficacy of typhoid conjugate vaccines [Electronic resource] // World Health Organization. – Mode of access: https://www.who.int/immunization/diseases/typhoid/ru/. – Date of access: 15.07.2019.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Typbar-TCV® Prequalification: Questions and Answers [Electronic resource] // Coalition against typhoid. – Mode of access: http://www.coalitionagainsttyphoid.org/policy-advocacyto-take-on-typhoid/typbar-tcv-prequalification-questionsand-answers. – Date of access: 15.07.2019.</mixed-citation><mixed-citation xml:lang="en">Typbar-TCV® Prequalification: Questions and Answers [Electronic resource] // Coalition against typhoid. – Mode of access: http://www.coalitionagainsttyphoid.org/policy-advocacyto-take-on-typhoid/typbar-tcv-prequalification-questionsand-answers. – Date of access: 15.07.2019.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Typhoid [Electronic resource] // World Health Organization. – Mode of access: https://www.who.int/news-room/fact-sheets/detail/typhoid. – Date of access: 15.07.2019.</mixed-citation><mixed-citation xml:lang="en">Typhoid [Electronic resource] // World Health Organization. – Mode of access: https://www.who.int/news-room/fact-sheets/detail/typhoid. – Date of access: 15.07.2019.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
