milmedВоенная медицинаMilitary Medicine2074-5044Белорусский государственный медицинский университетmilmed-744Research ArticleОРИГИНАЛЬНЫЕ НАУЧНЫЕ ПУБЛИКАЦИИ. Новые технологии в медицинеORIGINAL SCIENTIFIC PUBLICATIONS. New technologies in medicineКонсервация почечных трансплантатов в условиях статического холодового хранения: современное состояние проблемыConservation of kidney transplantas in the conditions of static cold storage: modern condition of the problemКирковскийЛ. В.KirkovskyL. V.ФедорукД. А.FedorukD. A.СадовскийД. Н.SadouskiD. N.ФедорукА. М.FedorukA. M.КалачикО. В.KalachikO. V.РуммоО. О.RummoO. O.ГУ «Минский научно-практический центр хирургии, трансплантологии и гематологии»Belarus201925102026044550Copyright © Кирковский Л.В., Федорук Д.А., Садовский Д.Н., Федорук А.М., Калачик О.В., Руммо О.О., 20262026Кирковский Л.В., Федорук Д.А., Садовский Д.Н., Федорук А.М., Калачик О.В., Руммо О.О.Kirkovsky L.V., Fedoruk D.A., Sadouski D.N., Fedoruk A.M., Kalachik O.V., Rummo O.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://milmed.ejournal.by/jour/article/view/744

Представлены актуальные сведения по проблеме консервации почечных трансплантатов. Приведены данные о донорах органов, их разновидности. Описаны основные клеточные механизмы при холодовой консервации, отмечены положительные и отрицательные эффекты. Отражены факторы риска и причины возникновения отсроченной функции и отторжения трансплантата почки. Описаны характеристики растворов для холодовой консервации органов.Цельсиор является внеклеточным раствором. Он был первично разработан для трансплантации сердца. Он содержит высокую концентрацию натрия с гистидином в виде буфера, лактобионат и маннитол для предотвращения отёка и глутатион в качестве антиоксиданта. Раствор сейчас используется при трансплантации сердца, печени, поджелудочной железы и почек.

Described preservation of renal grafts actual problems. Data on organ donors, their varieties are given. The basic cellular mechanisms during cold preservation are noted, it`s positive and negative effects are identified. Reflected risk factors and causes of delayed function and rejection of a kidney transplant. Described characteristics of solutions for cold preservation of organs.Celsior is also an extracellular solution. It was originally developed for heart transplantation. It contains a high concentration of sodium with histidine as a buffer, lactobionate and mannitol to prevent swelling and glutathione as an antioxidant. The solution is now used in heart, liver, pancreas and kidney transplants.

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The authors declare that there are no conflicts of interest present.