<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">milmed-754</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>Комплексное лечение гипотиреоидной комы</article-title><trans-title-group xml:lang="en"><trans-title>Complex treatment of the hypothyroid coma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобанова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobanova</surname><given-names>M. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Минский государственный медицинский колледж» ;&#13;
3-я городская клиническая больница им. Е. В. Клумова г. Минска</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>115</fpage><lpage>119</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лобанова М.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лобанова М.В.</copyright-holder><copyright-holder xml:lang="en">Lobanova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/754">https://milmed.ejournal.by/jour/article/view/754</self-uri><abstract><p>Гипотиреоидная кома (ГТК) – крайне тяжелое осложнение длительно некомпенсированного гипотиреоза, при котором летальность достигает 50–80 %. Впервые симптомы гипотиреоза у детей Th. B. Curling описал в 1850 г., в 1874 г. W. W. Gull дал описание гипотиреоза у взрослых. В 1878 г. W. M. Ord на базе морфологического исследования обнаружил атрофию щитовидной железы со следственными явлениями слизистого отёка кожи и подкожной клетчатки, что было названо микседемой. Гипотиреоидная кома (микседематозная) была описана в 1879 году.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лобанова, М. В. Комплексное лечение гипотиреоза. Военная медицина, 2016, № 4, стр. 134–140.</mixed-citation><mixed-citation xml:lang="en">Лобанова, М. В. Комплексное лечение гипотиреоза. Военная медицина, 2016, № 4, стр. 134–140.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Benfar, G, de Vincentiis, M. Postoperative airway obstruction: a complication of a previously undiagnosed hypo­­thyroidism. Otolaryngol Head Neck Surg 2005;132:343–4.</mixed-citation><mixed-citation xml:lang="en">Benfar, G, de Vincentiis, M. Postoperative airway obstruction: a complication of a previously undiagnosed hypo­­thyroidism. Otolaryngol Head Neck Surg 2005;132:343–4.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cullen, M. J., Mayne P. D., Sliney I. Myxoedema coma. Ir J Med Sci 1979;148:201–6.</mixed-citation><mixed-citation xml:lang="en">Cullen, M. J., Mayne P. D., Sliney I. Myxoedema coma. Ir J Med Sci 1979;148:201–6.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Fliers, E., Wiersinga, W. M. Myxedema coma. Rev Endocr Metabol Disord 2003;4:137–41.</mixed-citation><mixed-citation xml:lang="en">Fliers, E., Wiersinga, W. M. Myxedema coma. Rev Endocr Metabol Disord 2003;4:137–41.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Hylander, B, Rosenqvist, U. Treatment of myxoedema coma: factors associated with fatal outcome. Acta Endocrinol (Copenh) 1985;108:65–71.</mixed-citation><mixed-citation xml:lang="en">Hylander, B, Rosenqvist, U. Treatment of myxoedema coma: factors associated with fatal outcome. Acta Endocrinol (Copenh) 1985;108:65–71.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">MacKerrow, S. D., Osborn L. A., Levy H., et al. Myxe­dema–associated cardiogenic shock treated with intravenous triiodothyronine. Ann Intern Med 1992;117:1014–5.</mixed-citation><mixed-citation xml:lang="en">MacKerrow, S. D., Osborn L. A., Levy H., et al. Myxe­dema–associated cardiogenic shock treated with intravenous triiodothyronine. Ann Intern Med 1992;117:1014–5.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Malik, R., Hodgson, H. Quart. The relationship between the thyroid gland and the liver J. Med. – 2002. – Vol. 95. – № 9. – P. 559–569.</mixed-citation><mixed-citation xml:lang="en">Malik, R., Hodgson, H. Quart. The relationship between the thyroid gland and the liver J. Med. – 2002. – Vol. 95. – № 9. – P. 559–569.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Nicoloff, J. T., LoPresti, J. S. Myxedema coma: a form of decompensated hypothyroidism. Endocrinol Metab Clin North Am 1993;22:279–90.</mixed-citation><mixed-citation xml:lang="en">Nicoloff, J. T., LoPresti, J. S. Myxedema coma: a form of decompensated hypothyroidism. Endocrinol Metab Clin North Am 1993;22:279–90.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Reinhardt, W, Mann, K. Incidence, clinical picture, and treatment of hypothyroid coma: results of a survey. Med Klin 1997;92:521–4.</mixed-citation><mixed-citation xml:lang="en">Reinhardt, W, Mann, K. Incidence, clinical picture, and treatment of hypothyroid coma: results of a survey. Med Klin 1997;92:521–4.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ringel, M. D. Management of hypothyroidism and hyperthyroidism in the intensive care unit. Crit Care Clin 2001;17:59–74.</mixed-citation><mixed-citation xml:lang="en">Ringel, M. D. Management of hypothyroidism and hyperthyroidism in the intensive care unit. Crit Care Clin 2001;17:59–74.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rodriguez, I., Fluiters, E., Perez–Mendez L. F., et al. Factors associated with mortality of patients with myxoedema coma: prospective study in 11 cases treated in a single institution. J Endocrinol 2004;180:347–50.</mixed-citation><mixed-citation xml:lang="en">Rodriguez, I., Fluiters, E., Perez–Mendez L. F., et al. Factors associated with mortality of patients with myxoedema coma: prospective study in 11 cases treated in a single institution. J Endocrinol 2004;180:347–50.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Turhan, N. O., Kockar, M. C., Inegol, I. Myxedematous coma in a laboring woman suggested a pre–eclamptic coma: a case report. Acta Obstet Gynecol Scand 2004;83:1089–91.</mixed-citation><mixed-citation xml:lang="en">Turhan, N. O., Kockar, M. C., Inegol, I. Myxedematous coma in a laboring woman suggested a pre–eclamptic coma: a case report. Acta Obstet Gynecol Scand 2004;83:1089–91.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Wall, C. R. Myxedema coma: diagnosis and treatment. Am Fam Phys 2000;62:2485–90.</mixed-citation><mixed-citation xml:lang="en">Wall, C. R. Myxedema coma: diagnosis and treatment. Am Fam Phys 2000;62:2485–90.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Wartofsky, L. Myxedema, Coma. A Department of Me­dicine, Washington Hospital Center, Washington, DC 20010– 2975, USA, 2005.</mixed-citation><mixed-citation xml:lang="en">Wartofsky, L. Myxedema, Coma. A Department of Me­dicine, Washington Hospital Center, Washington, DC 20010– 2975, USA, 2005.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto, T., Fukuyama, J., Fujiyoshi, A. Factors asso­ciated with mortality of myxedema coma: report of eight cases and literature survey. Thyroid 1999;9:1167–74.</mixed-citation><mixed-citation xml:lang="en">Yamamoto, T., Fukuyama, J., Fujiyoshi, A. Factors asso­ciated with mortality of myxedema coma: report of eight cases and literature survey. Thyroid 1999;9:1167–74.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto, T. Delayed respiratory failure during the treatment of myxedema coma. Endocrinol Jpn 1984;31:769–75.</mixed-citation><mixed-citation xml:lang="en">Yamamoto, T. Delayed respiratory failure during the treatment of myxedema coma. Endocrinol Jpn 1984;31:769–75.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Zwillich, C. W., Pierson, D. J., Hofeldt F. D., et al. Ventilatory control in myxedema and hypothyroidism. N. Engl J. Med 1975; 292:662–5.</mixed-citation><mixed-citation xml:lang="en">Zwillich, C. W., Pierson, D. J., Hofeldt F. D., et al. Ventilatory control in myxedema and hypothyroidism. N. Engl J. Med 1975; 292:662–5.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
