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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">milmed-839</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Генетические механизмы шизофрении</article-title><trans-title-group xml:lang="en"><trans-title>Genetic mechanisms of schizophrenia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Девялтовская</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Devyaltovskaya</surname><given-names>M. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голоенко</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Goloenko</surname><given-names>I. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скугаревский</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skugarevsky</surname><given-names>O. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ «Республиканский научно-практический центр «Мать и дитя»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГНУ «Институт генетики и цитологии НАН Беларуси»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-3"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>2</issue><fpage>118</fpage><lpage>126</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Девялтовская М.Г., Голоенко И.М., Скугаревский О.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Девялтовская М.Г., Голоенко И.М., Скугаревский О.А.</copyright-holder><copyright-holder xml:lang="en">Devyaltovskaya M.G., Goloenko I.M., Skugarevsky O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/839">https://milmed.ejournal.by/jour/article/view/839</self-uri><abstract><p>В статье авторы проводят обзор современных подходов к объяснению генетической детерминации шизофрении, которая имеет сложный многоуровневый нелинейный характер. Отражена эволюция взглядов на связь генов и шизофрении в контексте влияния гипотетических средовых факторов.Обсуждаются различные методологические подходы к исследованиям роли генетических факторов шизофрении в сравнительном ключе, поднимаются проблемные вопросы таких исследований с концептуальных позиций. Аналитический обзор построен на упоминании литературных данных, являющихся первоисточником разных идеологических подходов к интерпретации роли генов в возникновение шизофрении.</p></abstract><trans-abstract xml:lang="en"><p>In the article, the authors review modern approaches to explaining the genetic determination of schizophrenia, which has a complex multi-level nonlinear character. The evolution of views on the relationship of genes and disease in the context of the influence of hypothetical environmental factors is reflected. Various methodological approaches to studying the role of genetic factors of schizophrenia in a comparative vein are discussed, and problematic issues of such studies are raised from a conceptual perspective.An analytical review is based on the mention of literature data, which are the primary source of various ideological approaches to the interpretation of the role of genes in the occurrence of schizophrenia.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>генетические механизмы</kwd><kwd>шизофрения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>genetic mechanisms</kwd><kwd>schizophrenia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Van der Merwe C., Passchier R., Mufford M. et al. 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