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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">milmed-901</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ НАУЧНЫЕ ПУБЛИКАЦИИ. Лечебно-профилактические вопросы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL SCIENTIFIC PUBLICATIONS. Medical and preventive questions</subject></subj-group></article-categories><title-group><article-title>Локальная и системная концентрация реагинов при круглогодичном аллергическом рините</article-title><trans-title-group xml:lang="en"><trans-title>Local and systemic concentration of reagins in perennial allergic rhinitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сакович</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sakovich</surname><given-names>A. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>29</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>37</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сакович А.Р., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Сакович А.Р.</copyright-holder><copyright-holder xml:lang="en">Sakovich A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/901">https://milmed.ejournal.by/jour/article/view/901</self-uri><abstract><p>Исследована концентрация реагинов в назальном секрете при круглогодичном аллергическом рините, которая составила 118,87 (90,50; 147,24) МЕ/мл, что достоверно выше (p &lt; 0,001), чем у здоровых лиц. Параллельно исследована концентрация реагинов в сыворотке крови, которая составила 132,34 (124,47; 190,21) МЕ/мл, что также достоверно выше (p &lt; 0,001), чем у здоровых лиц. В ходе исследования не установлено корреляций между концентрацией реагинов как в назальном секрете, так и в сыворотке крови и длительностью круглогодичного аллергического ринита, а также степенью тяжести его симптомов. При этом вероятность выявления диагностически значимой концентрации реагинов (более 100 МЕ/мл) у пациентов с круглогодичным аллергическим ринитом в сыворотке крови (ОR = 90,0) значительно превышала аналогичный показатель для назального секрета (ОR = 23,3).</p></abstract><trans-abstract xml:lang="en"><p>The concentration of reagins in nasal secretions in perennial allergic rhinitis was investigated, which was 118.87 (90.50; 147.24) IU / ml, which is significantly higher (p &lt; 0.001) than in healthy individuals. In parallel, the concentration of reagins in the blood serum was investigated, which was 132.34 (124.47; 190.21) IU / ml, which is also significantly higher (p &lt;0.001) than in healthy individuals. During the study, no correlations were found between the concentration of reagins in both nasal secretions and serum and the duration of perennial allergic rhinitis, as well as the severity of its symptoms. At the same time, the probability of detecting a diagnostically significant concentration of reagins (more than 100 IU / ml) in patients with perennial allergic rhinitis in the blood serum (OR = 90.0) significantly exceeded the same indicator for nasal secretions (OR = 23.3).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергический ринит</kwd><kwd>круглогодичный аллергический ринит</kwd><kwd>иммуноглобулин Е</kwd><kwd>реагины</kwd><kwd>назальный секрет</kwd><kwd>энтопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>allergic rhinitis</kwd><kwd>perennial allergic rhinitis</kwd><kwd>immunoglobulin E</kwd><kwd>regains</kwd><kwd>nasal secret</kwd><kwd>entopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Allergic Rhinitis and its impact on Asthma (ARIA) Guidelines-2016 Revision / Bousquet J. 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Entopy: localized mucosal allergic disease in the absence of systemic responses for atopy // Clin Exp Allergy 2003 Oct:33(10):1374–9.</mixed-citation><mixed-citation xml:lang="en">Powe D. G., Jagger C., Kleinjan A., Carney A. S., Jenkins D., Jones N. S. Entopy: localized mucosal allergic disease in the absence of systemic responses for atopy // Clin Exp Allergy 2003 Oct:33(10):1374–9.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
