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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">milmed</journal-id><journal-title-group><journal-title xml:lang="ru">Военная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Military Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5044</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/2074-5044.2025.4.90</article-id><article-id custom-type="elpub" pub-id-type="custom">milmed-95</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Хронические критические состояния</article-title><trans-title-group xml:lang="en"><trans-title>Chronic clinical illness (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лендин</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lendin</surname><given-names>N. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзядзько</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzyadzko</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нестеров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesterov</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нестерова</surname><given-names>Д. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesterova</surname><given-names>D. D.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кадушкин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kadushkin</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шубина</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shubina</surname><given-names>S. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кринчик</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Krinchik</surname><given-names>T. Y.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «Минский научно-практический центр хирургии, трансплантологии и гематологии»</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>State Institution «Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology»</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Educational Institution «Belarusian State Medical University»</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>22</day><month>08</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>90</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лендин Н.И., Дзядзько А.М., Нестеров В.В., Нестерова Д.Д., Кадушкин А.Г., Шубина С.Н., Кринчик Т.Ю., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лендин Н.И., Дзядзько А.М., Нестеров В.В., Нестерова Д.Д., Кадушкин А.Г., Шубина С.Н., Кринчик Т.Ю.</copyright-holder><copyright-holder xml:lang="en">Lendin N.I., Dzyadzko A.M., Nesterov V.V., Nesterova D.D., Kadushkin A.G., Shubina S.N., Krinchik T.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://milmed.ejournal.by/jour/article/view/95">https://milmed.ejournal.by/jour/article/view/95</self-uri><abstract><p>Под рубрикой фенотипа «хроническое критическое состояние» объединены различные эндотипы: полинейромиопатия критических состояний, синдром приобретенной слабости в отделении интенсивной терапии, синдром персистирующего воспаления, иммуносупрессии и катаболизма (определение UF SCIRS Исследовательского центра сепсиса и критических заболеваний Университета Флориды [Fr. Moree et al, 2012].</p><p>Учитывая увеличение распространенности PICS у пациентов с хроническим критическим состоянием (а также количества повторных госпитализаций, инвалидности и смертности), существует острая необходимость в научных исследованиях таких состояний.</p><p>Цель работы: проанализировать данные литературных обзоров, касающихся новых аспектов знаний о хронических критических состояниях, в большей степени, синдрома последствий интенсивной терапии (PICS-CCI).</p></abstract><trans-abstract xml:lang="en"><p>The phenotype «chronic critical illness» includes various endotypes: critical illness polyneuromyopathy, acquired weakness syndrome in the intensive care unit, persistent inflammation, immunosuppression and catabolism syndrome (definition of the UF SCIRS Sepsis and Critical Illness Research Center of the University of Florida [Fr. Moree et al, 2012].</p><p>Considering the increasing prevalence of PICS in patients with chronic critical illness (as well as the number of rehospitalizations, disability and mortality), there is an urgent need for scientific research on such conditions.</p><p>The aim of the work: to analyze the data of literature reviews concerning new aspects of knowledge about chronic critical illness, to a greater extent, the syndrome of consequences of intensive care (PICS-CCI).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронические критические состояния</kwd><kwd>синдром последствий интенсивной терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic critical illness</kwd><kwd>intensive care outcomes syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ohl, K ., Tenbrock, K. Reactive oxygen species as regulators of MDSC-mediated immune suppression / K. Ohl, K. 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