References

milmed

Военная медицина

Military Medicine

2074-5044

Белорусский государственный медицинский университет

10.51922/2074-5044.2021.4.121

milmed-992

Research Article

ОБЗОРЫ И ЛЕКЦИИ

REVIEWS AND LECTURES

Ответы адаптивной системы иммунитета на SARS-COV-2

Responses of the adaptive system of immunity to SARS-COV-2

Цыганков

А. М.

Cygankov

A. M.

Янченко

В. В.

Yanchenko

V. V.

УО «Витебский государственный ордена Дружбы народов медицинский университет»Belarus

2021

01112026

04121128

2026

Цыганков А.М., Янченко В.В.

Cygankov A.M., Yanchenko V.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://milmed.ejournal.by/jour/article/view/992

Адаптивная система иммунитета (далее СИ) важна для борьбы с вирусными инфекциями. Основными компонентами адаптивной иммунной системы являются В-лимфоциты, CD4 и CD8 Т-лимфоциты. В статье нами был проанализированы публикации, посвященные гуморальным и клеточным ответам людей на инфицирование SARS-CoV-2. Болезнь COVID-19 привела к высокой заболеваемости и смертности во всем мире за короткий срок. Научные достижения в понимании новой болезни были необычайно быстрыми, что является свидетельством работы международного научного сообщества, как в академических, так и в промышленных кругах в крайне напряженных условиях. В этой статье мы рассмотрим нынешнее понимание ответов адаптивного иммунитета при COVID-19 и вакцинации. Следует учитывать, что иммунный ответ способствует не только защите хозяина, но и иммунопатологии. Получив ответы на вопросы, касающиеся адаптивного иммунного ответа на SARS-CoV-2, можно решать практические задачи, которые стоят перед специалистами здравоохранения и обществом.

The adaptive immune system is important for fighting viral infections. The main components of the adaptive immune system are B-lymphocytes, CD4 and CD8 T-lymphocytes. In this article we reviewed publications dealing with humoral and cellular responses in humans to SARS-CoV-2 infection. The COVID-19 disease in question has resulted in high morbidity and mortality worldwide in a short period of time. Scientific advances in understanding the new disease have been extraordinarily rapid, a testament to the work of the international scientific community, both in academia and industry, under extremely stressful conditions. In this article we will look at the current understanding of adaptive immunity responses in COVID-19 and vaccination. It should be borne in mind that the immune response contributes not only to host protection but also to immunopathology. By obtaining answers to questions concerning the adaptive immune response to SARS-CoV-2, the practical challenges facing health professionals and society can be addressed.

SARS-CoV-2COVID-19лимфоцитыадаптивный иммунный ответ

SARS-CoV-2COVID-19lymphocytesadaptive immune response

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The authors declare that there are no conflicts of interest present.