The problem of adhesion after surgical diseases on the abdominal organs remains extremely relevant despite the rapid development of new medical technologies and approaches to the diagnosis and treatment of surgical diseases. The formation of adhesions occurs during open surgical interventions and will differ only in the degree of severity and clinical manifestations. The article is devoted to the study of oxygenation of the peritoneal tissue in experimental adhesions of the abdominal cavity. Experimental studies were carried out on 95 outbred guinea pigs with simulated adhesive disease of the abdominal cavity. As a result of performing direct oximetry on the surface of the peritoneum in conditions of modeling adhesions of the abdominal cavity in laboratory animals, it was revealed that any of the models causes, to a greater or lesser degree, hypoxic changes in the peritoneum, thereby creating favorable conditions for the maturation of coarse-fibrous connective tissue. The impact on the peritoneum of any of the modeling factors caused a decrease in the partial pressure of oxygen in the intestinal wall by an average of 45%. The leveling of hypoxic changes on the surface of the peritoneum in the postoperative period is a method of preventing adhesions of the abdominal cavity.

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