HEART RATE VARIABILITY AND PITUITARY-ADRENAL FUNCTION IN PATIENTS WITH PSORIASIS
https://doi.org/10.51922/2074-5044.2023.4.43
Abstract
The study of heart rate variability and the function of the pituitary-adrenal axis was carried out in 91 patients with various forms of psoriasis.
The tension of the regulatory systems of the heart rhythm and disorders of the autonomic nervous system observed in conditions of an active orthostatic test were established.
Impairment of the autonomic nervous system was associated with high glucocorticoid and mineralocorticoid activity of the adrenal glands.
The difference in the heart rate, pituitary and adrenal hormones was revealed in patients with streptococcus-associated psoriasis and psoriasis without streptococcal association.
About the Authors
T. A. SikorskayaBelarus
A. P. Muzychenko
Belarus
M. V. Kachuk
Belarus
А. V. Sikorski
Belarus
N. V. Mikulchik
Belarus
References
1. Vliyanie na immunopatogenez psoriaza deficita endokrinno-metabolicheskih faktorov [The effect ofvitamin d on the biochemical pathways of the development of metabolic disorders in psoriasis (review article)] / O.V. Samburskaya [i dr.] // Allergologiya i immunologiya. – 2022. – № 1 (23). – S. 12–14.
2. Kubanov, A.A. Epidemiologiya psoriaza v Rossijskoj Federacii (po dannym registra) [Epidemiology of psoriasis in the Russian Federation (according to the register)] / A.A. Kubanov, E.V. Bogdanova // Vestnik dermatologii i venerologii. – 2022. – № 2 (98). – S. 33–41.
3. Mashina, M.V. Osobennosti patogeneza avtonomnoj i perifericheskoj nevropatii u bolnyh psoriazom [Features of the pathogenesis of autonomic and peripheral neuropathy in patients with psoriasis] / M.V. Mashina, A.S. Nesterov, L.A. Belova // Ulyanovskij mediko-biologicheskij zhurnal. – 2023. – № 1. – S. 63–73.
4. Metody issledovaniya serdechnogo ritma po dannym EKG: variabelnost serdechnogo ritma i dispersionnoe kartirovanie (Obzornaya statya) [Methods for studying heart rate according to ECG data: heart rate variability and dispersion mapping (Review article)] / E.M. Novikov [i dr.] // Kremlevskaya medicina. Klinicheskij vestnik. – 2019. – № 4. – S. 81–89.
5. Patrushev, A.V. Ochagovaya infekciya i techenie hronicheskih dermatozov: sovremennyj vzglyad na problem [Focal infection and the course of chronic dermatoses: a modern view of the problem] / A.V. Patrushev, A.V. Samcov, A.V. Suharev // Voenno-medicinskij zhurnal. – 2021. – № 2. – S. 45–52.
6. Psihodinamicheskie aspekty v issledovanii struktury lichnosti pacientov s psoriaticheskoj boleznyu [Psychodynamic aspects in the study of the personality structure of patients with psoriatic disease] / Syatkovskij, V.A. [i dr.] // Dermatologiya. Kosmetologiya. – 2023. – № 1 (9). – S. 29–39.
7. Sikorskaya, T.A. Sostoyanie proteinazno-ingibitornoj sistemy i uroven‘ endogennoj intoksikacii u pacientov s vulgarnym psoriazom [The state of the proteinase-inhibitory system and the level of endogenous intoxication in patients with psoriasis vulgaris] / T.A. Sikorskaya // Medicina. – 2015. – № 1 (88). – S. 19–26.
8. Soderzhanie adrenokortikotropnogo gormona v ekssudatah kozhnogo okna pri nekotoryh immunooposredovyh zabolevaniyah kozhi [The content of adrenocorticotropic hormone in exudates of the skin window in some immune-mediated skin diseases] / D.S. Zagreshenko [i dr.] // Medicina v Kuzbasse. – 2022. – № 4. – S. 49–52.
9. Sorokina, E.V. Rol kletok vrozhdennoj immunnoj sistemy pri psoriaze [The role of cells of the innate immune system in psoriasis] / E.V. Sorokina, I.V Bisheva // Vestnik dermatologii i venerologii. – 2022. – № 5 (98). – S. 59–64.
10. Frolov, A.V. Novyj vzglyad na normalizaciyu parametrov serdechno-sosudistoj sistemy [A new look at the normalization of parameters of the cardiovascular system] // Medicinskaya panorama. – 2003. – № 8. – S. 50–52.
11. Hlebnikova, A.N. Rol epidermalnyh lipidov v patogeneze psoriaza / A. N. Hlebnikova [The role of epidermal lipids in the pathogenesis of psoriasis] // Klinicheskaya dermatologiya i venerologiya. – 2020. – № 2 (19). – S. 231–234.
12. Brynina, A.V. Comorbid conditions in psoriasis / A.V. Brynina, D.R. Gimhan, A I. Wickramage // Journal of the Grodno State Medical University. – 2023. – № 1 (21). – Р. 12–18.
13. New aspects of the pathogenesis of psoriasis / A.S. Zhukov [et al.] // Vestnik Dermatologii i Venerologii. – 2022. – № 4 (98). – Р. 31–40.
14. Psoriasis, chronic tonsillitis, and biofilms: Tonsillar pathologic findings supporting a microbial hypothesis / Н. Allen [et al.] // Ear Nose Throat J. – 2020. – № 3 (97). – Р. 79–82.
15. Study on the Impact of Psoriasis on Quality of Life: Psychological, Social and Financial Implications / V. Bulat [et al.] // Psychiatr Danub. – 2020. – № 4 (32). – Р. 553–561.
Review
For citations:
Sikorskaya T.A., Muzychenko A.P., Kachuk M.V., Sikorski А.V., Mikulchik N.V. HEART RATE VARIABILITY AND PITUITARY-ADRENAL FUNCTION IN PATIENTS WITH PSORIASIS. Military Medicine. 2023;(4):43-54. (In Russ.) https://doi.org/10.51922/2074-5044.2023.4.43
JATS XML