Samples of platelet-rich plasma (PRP), which is a liquid substance, when applied to the wound surface in animals with induced diabetes (MD) locally is not recorded and partly flowed outside the wound. In this regard, the in vitro formation of gel studied samples of PRP in the presence of a number of components of Gelation in different volumetric ratios. As activators used: calcium chloride (10 % solution), calcium gluconate (10 % solution), aprotinin (5000 ED/ml), Thrombin (100 ED/ml). Gel time, studied the ability of the uniform distribution on the set square and the adhesive properties of the local commit. Developed convenient from the standpoint of Gelation time and method for forming gel adhesiveness of samples PRP. Found that optimal for use on skin wounds with MD models from the positions of Gelation and adhesiveness is a method of obtaining PRP gel by adding Thrombin 20 u/ml in the ratio of 2:1 in the presence of calcium gluconate.

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