Синдром обструктивного апноэ во сне (СОАС) относится не только к одному из факторов риска фибрилляции предсердий (ФП), но и к одной из причин непосредственного прогрессирования данной аритмии, приводящей нередко к летальному исходу. Воспалению отводится существенная роль в патогенезе как ФП так и СОАС. Исследование прогностического потенциала некоторых лабораторно-гематологических индексов воспаления у пациентов с фенотипом ФП и СОАС остается предметом дискуссий.  В настоящей статье на основании регрессионного анализа клинических, инструментальных показателей и лабораторных биомаркеров, отражающих патофизиологические механизмы развития и прогрессирования ФП при СОАС, выявлена совокупность независимых детерминант рецидивирования ФП (индекс системного воспаления, размер левого предсердия, фракция выброса левого желудочка, индекс апноэ/гипопноэ) и разработана математическая модель для прогнозирования возврата аритмии в однолетний срок после электроимпульсой терапии у данной категории пациентов: при расчетном значении уравнения 0,499 и более прогнозируется высокая вероятность наступления рецидива ФП с чувствительностью 82,35 %, специфичностью 86,21 %. Этот персонифицированный подход способствует решению задачи прогнозирования течения ФП у конкретного пациента (выделению тех лиц, которым угрожает дальнейшее прогрессирование аритмии) и дает возможность ориентировать клинициста на выбор оптимальной обоснованной терапии ФП при сопутствующем СОАС. 

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