Symptoms of chronic rhinitis significantly reduce quality of life and ability to work in patients. Inability of full nasal breathing disrupts sleeping and daytime activity and can lead to snoring and obstructive sleep apnea as well as acute and chronic diseases of other ENT organs. One of the disease progression aspects is the suppression of respiratory epithelium cilia of the nasal cavity and impaired mucociliary clearance (MCC) both as a result of chronic nasal obstruction and the ciliostatic effect of topical decongestants which patients often use unsupervised for self-treatment. 
The aim of the study was to evaluate the impact of vasomotor rhinitis on the quality of life of young patients through a comprehensive analysis of subjective data (SNOT-22 questionnaire) in relation to objective indicators of mucociliary clearance function impaired. 
Materials and methods: 108 young adults (18–25 years old) were examined: 55 with a diagnosis of vasomotor rhinitis (study group) and 53 without ENT pathology (control group). All participants underwent a comprehensive examination including a quality-of-life assessment using the validated SNOT-22 questionnaire (RUS) and an objective assessment of the MCC- functional state using the timed saccharin test. 
Results: the quality of life in young patients with vasomotor rhinitis was reduced by 7 times (Me (LQ; UQ) = 54 (43; 64) points) compared to the control group (Me (LQ; UQ) = 8 (0; 20) points; p < 0.001) and a statistically significant violation of MCC was established: the time of the saccharin test was Me (LQ; UQ) = 23.17 (16.35; 31.17) minutes which is 2.5 times higher than the control group Me (LQ; UQ) = 9.3 (5.13; 12.79) minutes, p < 0.001.  A strong direct correlation was established between subjective and objective indicators (Spearman coefficient  ρ = 0.78; p < 0.001) in the study group: the disturbance of MCC more pronounced and the quality of life of the patient with vasomotor rhinitis is worse. 
Conclusion. The combined use of the SNOT-22 questionnaire with the saccharin test is an informative method for assessing of vasomotor rhinitis severity and can be recommended as a screening patient to early diagnosis and timely correction of identified disorders.

1. Dinamika pervichnoy zabolevaemosti boleznyami organov dyihaniya vzroslogo naseleniya Respubliki Bela- rus (2008 – 2019 godyi): Analiz po prichinam [Dynamics of primary incidence of respiratory diseases in the adultpopulation of the Republic of Belarus (2008–2019): Analysis by causes] / T. N. Glinskaya [i dr.] // Voprosyi organizatsii i informatizatsii zdravoohraneniya. – 2020. – № 4. – S. 48–60.

2. Smirnov, T. A. Tuzhilina, K. V. Vasomotor Rhinitis in the Clinical Practice of a General Practitioner // Prakti- cheskaya pulmonologiya. – 2023. – №1. – S. 58–65. DOI: 10.24412/2409–6636–2023–12862

3. Lopatin, A. S., Varvyanskaya, A. V. Vazomotornyy rinit: sovremennyy vzglyad na problemu [Vasomotor rhinitis: a mo- dern approach to the problem] // Consilium Medicum. – 2008. – Vol. 10. – N. 3. – P. 114–118. – Rejim dostupa https://consilium.orscience.ru/2075-1753/article/view/92707/ru_RU. – Data dostupa 11.06.2026.

4. Kunelskaya, N. L. Allergicheskiy i vazomotornyiy rinit – universalnoe reshenie [Allergic and vasomotor rhinitis – a uni- versal solution] / N. L. Kunelskaya, YU. V. Luchsheva // Astma i allergiya. – 2016. – № 1. – S. 17–26.

5. Khasanov, U. S., Abdurakhimova, Sh. S. Topical issues of vasomotor rhinitis in children. Eurasian Journal of Oto- rhinolaryngology – Head and Neck Surgery. 2024;3(4):78–82. Https://doi.org/10.57231/j.ejohns.2024.3.4.014

6. Serebryakova, I. YU., Kim, I. A., Nosulya, E. V., Korob kin, A. S. Vasomotor rhinitis. The novdel diagnostic modalities. Russian Rhinology. 2018;26(4):40–44. Https://doi.org/ 10.17116/ rosrino20182604140

7. Mareev, G. O., Mareev, O. V., Bondarenko, A. A. Study of local mucociliary clearance in patients with vasomotor and allergic rhinitis with concomitant nasal septal deviation // Mejdunarodnyiy nauchno-issledovatelskiy jurnal. – 2025. – № 1 (151). DOI:https://doi.org/10.60797/IRJ.2025.151.32

8. Vasomotor rhinitis: an unsolved problem. Review of the speech of the D. P. Poliakov. Pediatrics. Consilium Medicum. 2019; 1: 29–32. DOI: 10.26442/26586630.2019.1.190340.

9. Makhachev, M. B., Polunin, M. M., Asmanov, A. I., Shabelnikova E. I. The state of mucociliary transport of the mucous membrane of the inferior turbinates in children after various types of vasotomy. Russian Bulletin of Otorhinolaryngology. 2024;89(4):26–29. (In Russ.). Https://doi.org/10.17116/otorino20248904126

10. Gurov, A. V., Yushkina, M. A., Muzhichkova, А. V. Possibilities of activation of mucociliary transport in patients with inflammatory diseases of the nose and paranasal sinuses. Meditsinskiy Sovet. 2024;18(7):92–97. (In Russ.) Https://doi.org/10.21518/ms2024–076.

11. Gurov, A. V., Yushkina, M. A. Adequate mucociliary clearance as a factor in the prevention and control of pu rulen- t-inflammatory pathology of the ENT organs. Meditsinskiy sovet = Medical Council. 2021;(6):29–34. (In Russ.) Doi: 10.21518/2079–701X-2021–6-29–34.

12. Shabalin, V. V., Zakharova, G. P., Ivanov, N. I., Alek- sanyan Yu. S. Multiparametric assessment of motor func- tion of the ciliated epithelium based on digital video micro- scopy in patients with vasomotor rhinitis. Pharmacology & Pharmacotherapy. 2025; 5: 58–64. DOI 10.46393/27132129_2025_5_58–64

13. Vokhidov, U. N., Razzokov, Zh. Kh. Comparison of va- rious treatment methods for vasomotor rhinitis. Eurasian Journal of Otorhinolaryngology – Head and Neck Surgery. 2024;3(1):25–32 https://doi.org/10.57231/j.ejohns.2024.3.1.004

14. Vladimirova, T. Yu., Martynova, A. B., Kurenkov, A. V., Mukhsikhachoyan, D. M. Efficacy of a fixed herbal com bination in acute rhinosinusitis with olfactory disorder. RMJ. 2026;1:43–49. DOI: 10.32364/2225–2282–2026–1-9.

15. Kuliakin, E. V. Cross-cultural adaptation and validation of the sino-nasal outcome test (SNOT-22) for russianspeaking patients with vasomotor rhinitis and postnasal drip / E. V. Kuliakin [et al] // Meditsinskiy jurnal. – 2021. – № 1. – S. 132–137.

16. Laberko, E. L. The method for the direct evaluation of the state of mucociliary clearance in the children / E. L. Laberko [et al] // Vestnik otorinolaringoogii. – 2015. – № 2. – S.40–44/ Doi: 10.17116/otorino201580240–44.

17. Metod opredeleniya veroyatnosti razvitiya zabo - le vaniy i patologicheskih sostoyaniy polosti nosa, vyizyiva- yuschih narushenie nosovogo tsikla: instruktsiya po prime- neniyu MZ RB, utv. 30 noyabrya 2018 g. (reg. № 113–1118) [Method for determining the likelihood of developing di se a ses and pathological conditions of the nasal cavity that ca use disruption of the nasal cycle: instructions for use MoH RB, approved November 30, 2018 (reg. No. 113–1118)] / N. I. Greben [i dr.] // Gosudarstvennoe uchrejdenie «Respublikanskiy nauchno-prakticheskiy tsentr otorinolaringologii». – Minsk, 2018. – Rejim dostupa: https://lor.by/wp-content/uploads/2026/04/metod_n.pdf – Data dostupa: 11.06.2026.