Enteroviruses are well-known causes of a wide range of infectious diseases, ranging from mild illnesses such as typical exanthema to severe conditions such as serous meningitis. Given the continued relevance of the disease, the potential for severe progression, and the lack of specific prophylaxis, epidemiological vigilance is necessary for enteroviral and its various forms. This article examines the clinical presentation of the most common forms of enteroviral infection.

1. Xie, Z., Khamrin, P., Maneekarn, N., Kumthip, K. Epidemiology of Enterovirus Genotypes in Association with Human Diseases // Viruses. – 2024. – Vol. 16. – № 7. – P. 1165.

2. Butakova, L. V. Enterovirusnaya infekciya: obzor situacii v mire na sovremennom etape v usloviyah aktivizacii migracionnyh processov / L. V. Butakova, O. E. Trocenko, E. Yu. Sapega // Zdorov’e naseleniya i sreda obitaniya. – 2018. – № 4 (aprel’). – S. 50–59.

3. Bondarenko, A. L., Abbasova, S., Tihomolova, E. G., Fursova, E. A., Kropanev, A. V., Ezhova, O. A., Karpuniche va, A. A., Musinskaya, A. V., Petrygina, E. A. Klinicheskie proyavleniya enterovirusnoj infekcii u vzroslyh na sovremennom etape // Vyatskij medicinskij vestnik. – 2012. – № 1 – C. 9–13.

4. Shakaryan, A. K. Enterovirusnaya infekciya: nekoto- rye klinicheskie aspekty / A. K. SHakaryan // Infekcionnye bolezni: Novosti. Mneniya. Obuchenie. – 2013. – № 4 (5) – C. 23–26.

5. Ter-Bagdasaryan, L. V. Kliniko-epidemiologicheskie aspekty enterovirusnoj infekcii / L. V. Ter-Bagdasaryan, A. I. Ratnikova, E. A. Sten’ko // Infekcionnye bolezni: Novosti. Mneniya. Obuchenie. – 2020. – № 1 (32) – C. 88–93.

6. Liu Y., Song Y., Liu F., Chen Y., Liu Y., Shi J., Li K., Yin Y., Liang Q., Liu N., Ming M., Hua L., Shi Q, Xu J., Yuan R., Li S., Zhang L., Zhao Y., Wang N., Zhang J., Zhang Y., Chang Z., Zhang Z. Effectiveness of the enterovirus A71 vaccine on hand, foot, and mouth disease: a real-world study in China. Clin Microbiol Infect. 2025 Feb;31(2):258–265. doi: 10.1016/j.cmi.2024.09.020.

7. Kanaeva O. I. Enterovirusnaya infekciya: mnogoobrazie vozbuditelej i klinicheskih form / O. I. Kanaeva // Infekciya i immunitet. – 2014. – № 1. – C. 27–36.

8. Taktika vracha – infekcionista: prakticheskoe rukovod stvo: v 2 ch. / pod red. N. D. YUshchuka. – Moskva: GEOTAR-Media, 2021. – CH. 2. – 272 s.

9. Anohin, V. A. Enterovirusnye infekcii: sovremennye osobennosti / V. A. Anohin, A. M. Sabitova, I. E. Kravchenko, T. M. Martynova // Prakticheskaya medicina. – 2014. – № 9 (85) – C. 52–59.

10. Shevcova, N. P. Nevrologicheskie proyavleniya enterovirusnoj infekcii / N. P. SHevcova, M. V. Golubeva // Detskie infekcii. – 2004. – № 3. – C. 49–52.

11. Zhu P., Ji W., Li D., Li Z., Chen Y., Dai B., Han S., Chen S., Jin Y., Duan G. Current status of hand-foot-andmouth disease. J Biomed Sci. 2023 Feb 24;30(1):15. doi: 10.1186/s12929–023–00908–4. PMID: 36829162; PMCID: PMC9951172.

12. Zhang, M., Wang, H., Tang, J., He, Y., Xiong, T., Li, W., Qu, Y., Mu, D. Clinical characteristics of severe neonatal enterovirus infection: a systematic review. BMC Pediatr. 2021 Mar 15;21(1):127. doi: 10.1186/s12887–021–02599-y. PMID: 33722228; PMCID: PMC7958388.