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Local and systemic concentration of reagins in perennial allergic rhinitis

Abstract

The concentration of reagins in nasal secretions in perennial allergic rhinitis was investigated, which was 118.87 (90.50; 147.24) IU / ml, which is significantly higher (p < 0.001) than in healthy individuals. In parallel, the concentration of reagins in the blood serum was investigated, which was 132.34 (124.47; 190.21) IU / ml, which is also significantly higher (p <0.001) than in healthy individuals. During the study, no correlations were found between the concentration of reagins in both nasal secretions and serum and the duration of perennial allergic rhinitis, as well as the severity of its symptoms. At the same time, the probability of detecting a diagnostically significant concentration of reagins (more than 100 IU / ml) in patients with perennial allergic rhinitis in the blood serum (OR = 90.0) significantly exceeded the same indicator for nasal secretions (OR = 23.3).

About the Author

A. R. Sakovich
УО «Белорусский государственный медицинский университет»
Belarus


References

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2. Пискунов, Г. З. Аллергический ринит – современное понимание проблемы / Г. З. Пискунов, И. Л. Лазаревич // Российская ринология. – 2009. – № 2. – С. 80–86.

3. Powe D. G., Jagger C., Kleinjan A., Carney A. S., Jenkins D., Jones N. S. Entopy: localized mucosal allergic disease in the absence of systemic responses for atopy // Clin Exp Allergy 2003 Oct:33(10):1374–9.


Review

For citations:


Sakovich A.R. Local and systemic concentration of reagins in perennial allergic rhinitis. Military Medicine. 2021;(1):37-40. (In Russ.)

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ISSN 2074-5044 (Print)