The aim of the study was to determine the relationship between neurological manifestations of degenerative disk disease, visceral pathology and temporal characteristics of pain syndrome with an assessment of the quality of life of patients. 50 patients with non-specific back pain were examined. Diagnostics of neurological manifestations of degenerative disk disease, concomitant visceral pathology, assessment of the quality of life according to the SF-36 questionnaire, testing according to the hospital scale of anxiety and depression HADS were carried out. Results: most patients achieve remission (66%), 34% of patients develop relapses of varying duration. In 44% of patients, there were no neurological manifestations of degenerative disk disease. In 50% of cases, concomitant visceral pathology was detected. 38% of patients were diagnosed with deviations on the HADS scale. The duration of pain syndrome over one year significantly affected the decrease in the physical component of health according to the SF-36 questionnaire. The indicators of work activity (56%), daily activity due to the intensity of pain (44%) and emotional state (30%) deteriorated the most. This dictates the need to introduce an individual, integrated, multidisciplinary approach in the management of patients with vertebral pain syndrome in degenerative disk disease of the spine.

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