Despite the development of modern methods of diagnosis and treatment of obliterating atherosclerosis of the lower extremities in 38-65% of patients, the disease progresses with the development of critical ischemia of the lower extremities. This often requires amputation at various levels. Postoperative mortality in this case reaches 20% or more. The aim of this work was to study the causes of death in patients after amputation of the lower extremities for critical ischemia. We studied 296 medical records and 52 autopsy reports of the deceased, which were used to amputate the lower extremities. It turned out that the mortality rate in women is 1.9 times higher than in men. The risk of death is increased by the presence of coronary heart disease in a patient with grade 2B circulatory failure and atrial fibrillation. The most common immediate cause of death after amputation is multiple organ failure.

1. Moler, E. R. Zabolevaniya perifericheskih arterij / E. R. Moler, Dzhaffa M. R. - M.: GEOTAR-Media, 2010. – 224 s.

2. Christopher J. L. Murray GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016. Vol. 388 (10053). P. 1545–1602.

3. Nacional‘nye rekomendacii po vedeniyu pacientov s zabolevaniyami arterij nizhnih konechnostej / Rossijskoe obshchestvo angiologov i sosudistyh hirurgov, Associaciya serdechno-sosudistyh hirurgov Rossii, Rossijskoe nauchnoe obshchestvo rentgenendovaskulyarnyh hirurgov i intervencionnyh radiologov, Vserossijskoe nauchnoe obshchestvo kardiologov, Associaciya flebologov Rossii // 2013. – M. – S. 11–12.

4. Gostishchev, V. K. Prognozirovanie riska gnojno-nekroticheskih oslozhnenij amputacionnoj kul‘ti bedra / Gostishchev V. K., Lipatov K. V., Asatryan A. G., Vvedenskaya O. V. // Hirurgiya. ZHurnal im. N. I. Pirogova. – 2013. – № 11. – S. 4–8.

5. Baumann, F. Infrapopliteal lesion morphology in patients with critical limb ischemia: implications for the development of anti-restenosis technologies / Baumann F., Engelberger R. P., Willenberg T., et al. // J Endovasc Ther. – 2013; 20(2): 149–156

6. Soroka, V. V. Prognozirovanie klinicheskih iskhodov u pacientov s kriticheskoj ishemiej nizhnih konechnostej, perenesshih vysokuyu amputaciyu / Soroka V. V., Nohrin S. P., Ryazanov A. N., Belousov E. Yu., Petrivskij S. V. // Materialy XXIX Mezhdunarodnoj konferencii «Novye napravleniya i otdalennye rezul‘taty otkrytyh i endovaskulyarnyh vmeshatel‘stv v lechenii sosudistyh bol‘nyh. – Ryazan‘, 2014. – S. 331–332.

7. Paulus, N. Primary and secondary amputation in criti­ cal limb ischemia patients: different aspects / Paulus N., Jacobs M., Greiner A. // Acta Chir Belg.– 2012. 112 (4): 251-4.

8. Henry, A. J. Factors predicting resource utilization and survival after major amputation. / Henry A. J., Hevelone N. D., Hawkins A. T., Watkins M. T., Belkin M., Nguyen L. L. // J Vasc Surg. – 2013; 57 (3): 784-90.