The lecture contains the background about the development of the human during embryonic and early postembryonic periods of ontogenesis. The main part of the lecture is concerned with the basic data about the sources of primordia’s forming of the skull: sclerotomes of the mesoderm’s somites and nerve crest cells that migrate into the regions of the skull primordia; about differentiation processes in skull: intramembranous ossification as the example of the parietal bone development, endochondral ossification as the example of basic and lateral parts of the occipital bone development and the main stages of both types of ossification and cells taking part in bone forming. The information about the rebuilding of the human skull during early postembryonic period and about humoral factors regulating resorption and forming bone tissue for maintain homeostasis of mineral substances in the organism is provided.

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