Natural medicine and the problem of hepatoprotection
Abstract
In the last decade, the interest of researches and consumers to the impact of bioactive diet on human health and its widespread use in everyday life for prevention and treatment of many chronic diseases has increased. It was found that the most successful was the use of natural medicine – bioactive foods, mainly plant origin – in liver diseases (in 81%). The increase in the incidence of chronic liver pathologies is called the second epidemic of our century. In presenting our review of the data of modern foreign studies, we focused attention on the mechanisms of exposure to nutrients of natural food products – those with hepatoprotective properties, safe and without negative side effects, and which are recommended to be included in diet, especially at high risk of chronic liver diseases.
About the Authors
A. T. BykovRussian Federation
Yu. M. Ambalov
Russian Federation
T. N. Malyarenko
Russian Federation
References
1. Baliga M. S., Shivashankara A. R., Thilakchand K. R., et al. Scientific validation of the hepatoprotective effects of the Indian Goosberry: a review / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013. – Ch. 45. – P. 697–708.
2. Byrne С.D. Fatty liver: role of inflammation and fatty acid nutrition // Prostaglandins, Leukotrienes, and Essential Fatty Acids. – 2010. – Vol. 82. – No. 4–6. – P. 265–271.
3. Сentis E., Marzocchi R., Di Domizio S., et al. The effect of lifestyle changes in nonalcoholic fatty liver disease // Digestive Diseases. – 2010. – Vol. 28. – No. 1. – P. 267-273.
4. Daniel L. Global burden of hepatitis C // Liver International. – 2009. – Vol. 29. – P. 74–81.
5. Dowman J. K., Armstrong M. J., Tomlinson J. W., et al. Current therapeutic strategies in nonalcoholic fatty liver disease // Diabetes, Obesity & Metabolism. – 2011. – Vol. 13. – No. 8. – P. 692–702.
6. Ebeid H. M., Gibriel A. A., Al-Sayed H. M., et al. Hepatoprotective and oxidant effects of wheat, carrot, and mango as nutraceutical agents against CCI4-induced hepatocellular toxicity // Am. Coll. Nutr. – 2015. – Vol. 34. – No. 3. – P. 228–231.
7. Elias M. C., Parise E. R., de Carvalho L., et al. Effect of 6 month nutritional intervention on nonalcoholic fatty liver disease // Nutr. – 2010. – Vol. 26. – No. 1112. – P. 1094–1099.
8. Ezaela C. C, Nweke L. N., Unekwe P. C., et al. Fresh garlic extract protects the liver against acetaminophen-induced toxicity // International J. Nutr. – 2009. – Vol. 7. – No. 1. – P. 253–263.
9. Fahmy N. M., Al-Sayed E., Abdel-Daim M. M., et al. Protective effect of Terminalia muelleri against carbon tetrachlorideinduced hepato- and nephro-toxicity in mice and characterization of its bioactive constituens // Pharm. Biol. – 2016. – Vol 54. – P. 303–313.
10. Freedman N. D., Everhart J. E., Lindsay K. L., et al. Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C // Hepathol. – 2009. – Vol. 50. P. 1360–1369.
11. Genoni A., Lo J., Lyons-Wall Ph., Devine A. Compliance, palatability and feasibility of PALEOLITHIC and Australial Guide to healthy eating diets in healthy women: a 4-week dietary intervention // Nutrients. – 2016. – Vol. 8. – P. 481–487.
12. Guo G., Sun J., He H., et al. Antihepatotoxic effect of corn peptides against Bacillus Calmette-Guerin / lipopolysaccharideinduced liver injury in mice // Food and Chemical Technology. – 2009. – Vol. 47. – P. 2431–2435.
13. Hegazi R. A., Seth A. The role of curcumin in gastrointestinal and liver diseases / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013a. – Ch. 38. – P. 585-596.
14. Hegazi R. A., Seth A. The role of prebiotics in gastrointestinal and liver diseases / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal dis- ease. – 2013b. – Ch. 37. – P. 569-583.
15. Kampkotter A., Wiegand C., Timpel C., et al. Increased expression of catalase in human hepatoma cells by the soy isoflavone, diadzein // Basic & Clinical Pharmacology & Toxicology. – 2008. – Vol. 102. – P. 437-442.
16. Kresser Ch. Paleo Troubleshooters Guide (a). Food addivities: harmful or harmless? (b) // Chris Kresser L. Ac. – 2014. – 38 p. (а); 22 р. (b).
17. Kurachashi N., Inoue M., Iwasaki M., et al. Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan // Br. J. Cancer. – 2009. – Vol. 100. – P. 181–184.
18. Lim T. K. Edible medicinal and non-medicinal plants. Vol. 9: Stems, roots, bulbs / Carrot. P. 374-416. – Springer DortlechtHeidelberg-New York-London. – 2015 – 1012 p.
19. Liu J., Yadev V. R., Aggarwal B. B., Nair M. G. Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxigenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B // Natural Product Communications. – 2010. – Vol. 5. – No. 8. – P. 1253–1257.
20. Minihane A. M., Vinoy S., Russell W. R., et al. Low-graid inflammation, diet composition and health: current research evidence and its translation // Brit. J. Nutr. – 2015. – Vol. 114. – P. 999–1012.
21. Miura D., Miura Y., Yagasaki K. Effect of apple polyphenol extracton hepatoma proliferation and invasion in culture and on tumor growth, metastasis, and abnotmal lipoprotein profiles in hepatoma-bearing rats // Biosci., Biotechnol., Biochem. – 2007. – Vol. 71. – P. 2743–2750.
22. Nishino H. M., Murakoshi M., Tokuda H., Satomi Y. Cancer prevention by carotenoids // Arch. Biochem., Biophys. – 2009. – Vol. 483. – P. 165–168.
23. Rašković A., Milanović I., Pavlović N., et al. Antioxidant activity of Rosemary (Rosemarinus officialis L.) essential oil and his hepatoprotective potential // BMC Complementary and Alternative Medicine. – 2014. – Vol. 14. – No. 225. – 9 p.
24. Samojlic I., Lacis N., Mimica-Dukic N., et al. Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum) // J. Agricultural and Food Chemistry. – 2010. – Vol. 15. – P. 8848–8853.
25. Sathiaraj E., Chutke M., Reddy M. Y., et al. A case control study on nutritional risk factors in nonalcoholic fatty liver disease in Indian population // Eur. J. Clin. Nutr. – 2011. – Vol. 65. – No. 4. – P. 533–537.
26. Sharma R. Biochemical mechanisms of fatty liver and bioactive foods: wild foods, bioactive foods, clinical trials in hepatoprotection / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013. – Ch. 46. – P. 709–741.
27. Sharp G. B., Lagarde F., Mizuno T., et al. Relationship of hepatocellular carcinoma to soya food consumption: a cohortbased, case-control study in Japan // Intern. J. Cancer. – 2005. – Vol. 10. – P. 290–295.
28. Shivashznkara A. R., Haniadka R., Fayad R. et al. Hepatoprotective effect of Zingiber officinale Roscoe (Ginger): a review / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013. – Ch. 42. – P. 657–671.
29. Shukla S. K., Kumar V. Bioactive foods and supplements for protection against liver diseases / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013. – Ch. 36. – P. 557–567.
30. Sugiura M. Carotenoids: liver diseases prevention / In: Watson R. R., Preedy V. R. (Eds). Bioactive food as dietary intervention for liver and gastrointestinal disease. – 2013. – Ch. 27. – P. 421–435.
31. Sullivan S. Implications of diet on nonalcoholic fatty liver disease // Curr. Opin. Gastroenterol. – 2010. – Vol. 26. – No. 2. – P. 160–164.
32. Yang J., Li Y., Wang F., Wu C. Hepatoprotective effect of apple polyphenols on CCL4 induced acute liver damage in mice // J. Agricult a. Food Chemistry. – 2010. – Vol. 10. – P. 6525–6531.
33. Yu M. H., Choi J. H., Chae I. G., et al. Suppression of LPSinduced inflammatory activities by Rosemarinus officinalis L. // Food.Chem. – 2013. – Vol. 136. – P. 1047–1054.
34. Watson R. R., Preedy V. R. (Eds.). Bioactive food as dietary intervention for liver and gastrointestinal disease / Academ. Press UK, USA. Elsevier Inc. – 2013. – 774 p.
35. Wells M. L., Potin Ph., Craigie J. S., et al. Algae as nutritional and functional food sources: revisiting our understanding // J. Appl. Phycol. 21 November 2016. Doi: 10.1007/s10811-016-09745.
36. Whalen K. A., McCullough M. L., Flanders W. D., et al. Paleolithic and Mediterranean diet pattern scores are inversely associated with biomarkers of inflammation and oxidative balance in adults // J. Nutr. – 2016 June. – Vol. 146. – No. 6. – P. 1217–1226.
37. Zakynthinos G., Varzakas T., Petsios D. Sea Buckthorn (Hippophae Rhamnoides) lipids and their functionality on health aspects // Curr. Res. Nutr. Food Sci. – 2016. – Vol. 4. – No. 2. – https://doi.org/10.12944/CRNFSJ.4.3.04.
38. Zarfeshany A., Asgary S., Javanmard S. H. Potent health effects of pomegranate // Adv. Biomed. Res. – 2014. – Vol. 3. – P. 100–107.
39. Zhang A., Sun H., Wang X. Recent advances in natural products from plants for treatment of liver diseases // Eur. J. Med. Chem. – 2013. – Vol. 63. – P. 570–577.
40. Zhu R., Wang Y., Guo Q. Oxidative stress in liver disease // Hepatol. Res. 2012. – Vol. 42. – P. 741–749.
Review
For citations:
Bykov A.T., Ambalov Yu.M., Malyarenko T.N. Natural medicine and the problem of hepatoprotection. Military Medicine. 2017;(4):82-89. (In Russ.)
JATS XML