An adapted method of nested RT-PCR for the detection of the hepatitis E virus has been described. A comparative characteristic of the proposed method with existing import analogues has been made. The high specificity of the method allowing to determine the HEV RNA in samples of blood serum, tissues and extracts of feces of various mammals, including humans, is shown. The high sensitivity of the proposed method, which has a low threshold level of detectable concentration of HEV of 10 IU/ml, is established.

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