Central venous catheters are widely used in intensive care. According to a number of literature sources, when used in 15% of patients develop various complications, of which infectious up to 26%, mechanical – up to 25%. The article reviews the literature sources, reveals the issues of the etiology, pathogenesis, diagnosis, prevention and treatment of bloodstream infections caused by the central venous catheter. In order to minimize the risk of developing infectious complications during their use for intensive care, it is recommended to: clearly determine the indications for setting and removing the catheter; prefer catheters impregnated with antibiotics and antiseptics with a minimum number of ports; prefer devices for seamless fixation and sterile transparent semi-permeable stickers; timely replacement of accessories for infusion; avoid frequent insufficiently justified fences through the catheter; strictly follow the rules of asepsis and antiseptics; when infectious complications are detected, prescribe antibacterial therapy in a timely manner and make a decision about changing or removing the catheter.

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