Subpopulation composition of synovial fluid in patients with osteoarthritis joints of large and medium-sized was studied. Fibroblast-like synoviocytes were identified in the synovial fluid of 68,2% of the patients. This indicates damage to the synovial membrane.
It was found that the quantitative content of T-cells and the ratio of their subpopulations indicates the presence of immune inflammation in the affected joint.

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