Acute fluid collection in acute pancreatitis
https://doi.org/10.51922/2074-5044.2026.2.111
Abstract
The classification, key pathogenetic mechanisms, clinical course and modern principles of surgical management of acute fluid collections complicating the course of acute pancreatitis are presented in this review.
Acute fluid collections are formed in acute pancreatitis in more than 50 % of cases, predetermining medium or severe course of the disease. Acute fluid collections are formed as a result of primary aseptic inflammatory edema in the zone of pancreatic gland destruction (early phase), aseptic sequestration with subsequent melting (liquefaction) of necrotized tissue (late phase) and violation of integrity of pancreatic duct system, which can occur at different terms from the onset of the disease.
Invasive treatment of acute fluid collections is indicated in case of their infection, persisting or first appeared organ failure, intra-abdominal hypertension, development of symptoms or complications. For invasive treatment of acute fluid collections percutaneous (under US or CT control), endoscopic (transmural or transpapillary) and operative (open or minimally invasive) interventions are used. They may be combined and/or performed sequentially. The probability of application of different methods of invasive management of acute fluid collections in each specific case determine the need for a multidisciplinary (with the participation of surgeons, anesthesiologists-resuscitators, radiation and endoscopic diagnostics doctors) approach to medical care for this pathology.
Meanwhile, up to now, clear and unambiguous indications for invasive management of acute fluid collections have not been evidently defined, the criteria of choosing the optimal terms, method, access and volume of intervention have not been regulated.
About the Author
A. V. Mazanik
432 Order of the Red Star Main Military Clinical Medical Center of the Armed Forces of the Republic of Belarus
Belarus
Belarus
Minsk
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Review
For citations:
Mazanik A.V. Acute fluid collection in acute pancreatitis. Military Medicine. 2026;(2):111-119. (In Russ.) https://doi.org/10.51922/2074-5044.2026.2.111
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