Autoimmune encephalitis (AE) is a severe but potentially curable disease of the central nervous system. One of the main representatives of AE is anti-NMDA receptor AE (autoimmune encephalitis with antibodies to NMDAtype glutamate receptors). The disease is characterized by polymorphic symptoms (neuropsychiatric disorders, dyskinesia, autonomic dysfunction), rapid progression with the development of life-threatening conditions requiring treatment in the intensive care unit (ICU) and a multidisciplinary approach in a multidisciplinary hospital. 
This article presents the results of our own clinical observations of the diagnosis and treatment of patients with anti-NMDA receptor AE who were urgently hospitalized in the intensive care unit and the neurology department of a multidisciplinary medical institution (State Institution «432 Order of the Red Star main military Clinical Medical Center of the Armed Forces of the Republic of Belarus») with a discussion of diagnostic features, intensive care, and the most significant aspects of pathogenetic and symptomatic treatment.

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