Modern aspects of diagnosis and treatment of mycobacteriosis of the lungs without bacterial release
Abstract
In the article there are the results of the examination of 54 patients (median age 61 years [49 years; 76 years]) with mycobacteriosis of the lungs. The diagnosis of mycobacteriosis was established according to the results of bacteriological examination of biopsy specimens. There were chronic nonspecific respiratory diseases in the case histories of 22.2% of patients. M. avium complex (MAC) were detected in 39 cases (72.2%) (95% CI 60.3–84.2), all the other types of non-tuberculous mycobacteria (NTMB) were 22.2% in total – they were detected in 12 patients (95% CI 11.1–33.3), mixed isolates were in 3 patients (5.5%) (95% CI –0.5–11.7). The clinical and bacteriological effectiveness of treatment were low enough (65.1%), especially in elderly patients with M. avium complex.
About the Authors
N. V. ManovickayaBelarus
G. L. Borodina
Belarus
M. I. Dusmikeeva
Belarus
B. A. Volynets
Belarus
D. I. Borodin
Belarus
References
1. Микобактериозы: современное состояние проблемы / В. Н. Зимина, С. Ю. Дегтярева, Е. Н. Белобородова, Е. И. Кулабухова, Л. И. Русакова, О. В. Фисенко // Клиническая микробиология и антимикробная химиотерапия. – 2017. – Том 19 (№ 4). – С. 276–282.
2. Микобактериозы легких: учебно-методическое пособие / Г. Л. Бородина [и др.] – Минск : БГМУ, 2018. – 28 с.
3. Brode, S. K. The epidemiologic relationship between tuberculosis and non-tuberculous mycobacterial disease: a systematic review. / S. K. Brode, C.L. Daley, T.K. Marras // Int. J. Tuberc. Lung Dis. – 2014. – Vol. 18 (11). – P. 1370–1377.
4. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases / D.E. Griffith [et al.] // Am J. Respir Crit Care Med. – 2007. – Vol. 175. – P. 367–416.
5. Epidemiology of Nontuberculous Mycobacterial Infection, South Korea, 2007–2016 / Hyewon Lee [et al.] // Emerging Infectious Diseases – 2019. – Vol. 25, № 3. www.cdc.gov/eid.
Review
For citations:
Manovickaya N.V., Borodina G.L., Dusmikeeva M.I., Volynets B.A., Borodin D.I. Modern aspects of diagnosis and treatment of mycobacteriosis of the lungs without bacterial release. Military Medicine. 2020;(4):42-47. (In Russ.)
JATS XML